Results 61 to 70 of about 2,864,260 (309)
Unobstructedness of filling secants and the Gruson-Peskine general projection theorem
, 2014 We prove an unobstructedness result for deformations of subvarieties constrained by intersections with another, fixed subvariety. We deduce smoothness and expected-dimension results for multiple-point loci of generic projections, mainly from a point or a
Ran, Ziv
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Tensor Transpose and Its Properties [PDF]
, 2014 Tensor transpose is a higher order generalization of matrix transpose. In this paper, we use permutations and symmetry group to define? the tensor transpose. Then we discuss the classification and composition of tensor transposes.
Pan, Ran
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
MiR-802 Suppresses Colorectal Cancer Cell Viability, Migration and Invasion by Targeting RAN
Cancer Management and Research, 2020 Hailong Feng,1 Lingling Liu,1 Laijing Xu,1 Haili Wang,1 Qiuju Hua,2 Peng He1 1Department of General Surgery, The First Affiliated Hospital of Xinxiang Medical University, Weihui City, Henan Province 453100, People’s Republic of China; 2Hospital of ...
Feng H, Liu L, Xu L, Wang H, Hua Q, He P
doaj
The Ran-Reurings fixed point theorem without partial order: a simple proof
, 2014 The purpose of this note is to generalize the celebrated Ran and Reurings fixed point theorem to the setting of a space with a binary relation that is only transitive (and not necessarily a partial order) and a relation-complete metric.
Ben-El-Mechaiekh, Hichem
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Canonical systems and their limits on stable curves
, 2013 We propose an object called 'sepcanonical system' on a stable curve $X_0$ which is to serve as limiting object- distinct from other such limits introduced previously- for the canonical system, as a smooth curve degenerates to $X_0$.
Caporaso +11 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source