Results 81 to 90 of about 10,982 (172)

Cdc25‐Mediated Activation of the Small GTPase RasB Is Essential for Hyphal Fusion and Symbiotic Infection of Epichloë festucae

Molecular Plant Pathology, Volume 27, Issue 1, January 2026.
A conserved Cdc25–RasB signalling pathway, essential for hyphal fusion and host infection, is repurposed in Epichloë festucae to maintain a stable mutualistic symbiosis with grass hosts. ABSTRACT Epichloë festucae is a filamentous endophytic fungus that symbiotically colonises the intercellular spaces of aerial tissues in perennial ryegrass without ...
Mariko Inagaki, Shota Kamiya, Ayane Okamura, Atsushi Miura, Yuka Kayano, Aiko Tanaka, Daigo Takemoto   +6 more
wiley   +1 more source

Selective knockout of murine glutamic acid‐rich protein 2 significantly alters dark continuous noise in rod photoreceptors

The Journal of Physiology, Volume 604, Issue 1, Page 460-478, 1 January 2026.
Abstract figure legend GARP2 has a minor role in maintaining the structural integrity of the rod outer segments as a function of age, but an important role in regulating rod photoreceptor continuous noise, likely through stabilization of PDE6 basal activity.
Delores A. Stacks, Ulisse Bocchero, Marci L. DeRamus, Mai N. Nguyen, Jeffrey Messinger, Timothy W. Kraft, Steven J. Pittler, Johan Pahlberg   +7 more
wiley   +1 more source

Guidance document on the submission of data for the evaluation of the safety and efficacy of substances for the removal of microbial surface contamination of foods of animal origin intended for human consumption

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract EFSA developed an updated guidance document on the submission of data for the evaluation of the safety and efficacy of decontaminating substances for the removal of microbial surface contamination of foods of animal origin intended for human consumption (referred to as ‘food’).
EFSA Panel on Food Contact Materials (FCM), Claude Lambré, Riccardo Crebelli, Maria de Silva, Konrad Grob, Evgenia Lampi, Maria Rosaria Milana, Marja Pronk, Gilles Rivière, Mario Ščetar, Georgios Theodoridis, Els Van Hoeck, Nadia Waegeneers, Declan Bolton, Sara Bover‐Cid, Joop de Knecht, David M. Gott, Alicja Mortensen, Luisa Peixe, Panagiotis Skandamis, Blanka Halamoda‐Kenzaoui, Winy Messens, Cristina Croera   +22 more
wiley   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel, Katrin M. Reitmeier, Emilia Kieckhöfer, Khawla Abualia, Duc Nguyen‐Minh, Mahsa Matin, Henning Hagmann, Richard J. M. Coward, Sebastian Brähler, Philipp Antczak, Bernhard Schermer, Thomas Benzing, Patrick Giavalisco, Paul T. Brinkkoetter   +13 more
wiley   +1 more source

Ran modulates allosteric crosstalk between importin β surfaces. [PDF]

Nat Commun
Ko YH, Li F, Suinn SS, Li J, Hou CD, Lokareddy RK, Cingolani G.   +6 more
europepmc   +1 more source

Viral interference of nucleocytoplasmic transport. [PDF]

J Biol Chem
Chien CY, Mobbs GW, Ehrenkranz J, Hoelz A.   +3 more
europepmc   +1 more source

Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase. [PDF]

Nat Commun
Baytshtok V, DiMattia MA, Lima CD.
europepmc   +1 more source

The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition. [PDF]

Mol Cell
Smith AM, Li Y, Velarde A, Cheng Y, Frankel AD.   +4 more
europepmc   +1 more source

The Human Omnibus of Targetable Pockets. [PDF]

J Cheminform
Carpenter KA, Altman RB.
europepmc   +1 more source

PCV2 Cap protein nuclear import via importin α/β receptor: molecular insights and antiviral potential. [PDF]

Front Microbiol
Lin C, Li N, Tao L, Li H, Ma J, Wu C, Zhang F, Fang S, Tan J, Huang Y, Zeng X, Zeng Y.   +11 more
europepmc   +1 more source