Results 91 to 100 of about 20,745 (303)

EEG-Based random number generators

open access: yes, 2017
In this paper, we propose a new method that transforms electroencephalogram (EEG) signal and its wave bands into sequences of bits that can be used as a random number generator.
Nguyen, Khoa   +7 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Real‐time seedless post‐processing for quantum random number generators

open access: yesIET Quantum Communication
Quantum‐proof randomness extraction is essential for handling quantum side information possessed by a quantum adversary, which is widely applied in various quantum cryptography tasks.
Qian Li, Hongyi Zhou
doaj   +1 more source

SOURCES OF RANDOMNESS FOR USE IN RANDOM NUMBER GENERATION

open access: yesInternational Journal of Computing, 2014
Efficient generation of random numbers plays significant role in cryptographic applications. Such a generator has to produce unpredictable and un-correlated random bits. Random number generators are classified as pseudo-random number generators (PRNGs) and true random number generators (TRNGs).
Anastasios Fragopoulos   +1 more
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Random Walks Arising in Random Number Generation

open access: yesThe Annals of Probability, 1987
Random number generators often work by recursively computing \(X_{n+1}\equiv aX_ n+b(mod p)\). Various schemes exist for combining these random number generators. In one scheme, a and b are themselves chosen each time from another generator. Assuming that this second source is truly random, we investigate how long it takes for \(X_ n\) to become random.
Chung, F. R. K.   +2 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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