Results 101 to 110 of about 20,745 (303)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Analysis and Guidelines for Different Designs of Pseudo Random Number Generators

IEEE Access
The design of an efficient Pseudo Random Number Generator (PRNG) with good randomness properties is an important research topic because it is a core component in many applications.
Sherif H. AbdELHaleem, Salwa K. Abd-El-Hafiz, Ahmed G. Radwan   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Computer system for selecting silicon diodes for random number generators

Технологія та конструювання в електронній апаратурі, 2006
A methodology is proposed for analyzing and selecting primary sources of impulsive noise for use in random number sequence generators. A description is given of a computer system designed to analyze the characteristics of noise pulse streams in diodes ...
А. K. Baranouski, P. V. Kuchinski, I. Z. Rutkowski   +2 more
doaj  

Pseudo-Random Number Generators for Stochastic Computing (SC): Design and Analysis

IEEE Open Journal of Nanotechnology
In most nanoscale stochastic computing designs, the Stochastic Number Generator (SNG) circuit is complex and occupies a significant area because each copy of a stochastic variable requires its own dedicated (and independent) stochastic number generator ...
Pilin Junsangsri, Fabrizio Lombardi
doaj   +1 more source

A Review on Applications of Chaotic Maps in Pseudo-Random Number Generators and Encryption. [PDF]

Ann Data Sci, 2022
Naik RB, Singh U.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Comparing pseudo- and quantum-random number generators with Monte Carlo simulations

APL Quantum
We study how the Monte Carlo simulations of the critical dynamics of two-dimensional Ising lattices are affected by the quality (as compared to true randomness) of the pseudo-randomness used in them by computing an observable known to be sensitive to it:
David Cirauqui, Miguel Ángel García-March, Guillem Guigó Corominas, Tobias Graß, Przemysław R. Grzybowski, Gorka Muñoz-Gil, J. R. M. Saavedra, Maciej Lewenstein   +7 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

From Continuous-Time Chaotic Systems to Pseudo Random Number Generators: Analysis and Generalized Methodology. [PDF]

Entropy (Basel), 2021
De Micco L, Antonelli M, Rosso OA.
europepmc   +1 more source