Results 121 to 130 of about 193,973 (281)

Some Difficult-to-pass Tests of Randomness [PDF]

We describe three tests of randomness-- tests that many random number generators fail. In particular, all congruential generators-- even those based on a prime modulus-- fail at least one of the tests, as do many simple generators, such as shift register
George Marsaglia, Wai Wan Tsang
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Quantum random number generators with entanglement for public randomness testing. [PDF]

Sci Rep, 2020
Jacak JE, Jacak WA, Donderowicz WA, Jacak L.   +3 more
europepmc   +1 more source

A Search for Good Pseudo-random Number Generators : Survey and Empirical Studies

, 2018
In today's world, several applications demand numbers which appear random but are generated by a background algorithm; that is, pseudo-random numbers. Since late $19^{th}$ century, researchers have been working on pseudo-random number generators (PRNGs).
Bhattacharjee, Kamalika, Das, Sukanta, Maity, Krishnendu   +2 more
core  

Random Number Generator

, 2011
AbstractMost modern encryption and authentication methods rely on generating random numbers for key generation, initial vectors, or nonces. A Random Number Generator is cryptographically secure if the sequences of numbers that it generates are unpredictable. They are typically grouped into two categories: Pseudo-Random Number Generators and True Random
openaire   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Security and Performance-Based Design and Evaluation Criteria for Cryptographic Random Number Generators

Firat University Journal of Experimental and Computational Engineering
This study comprehensively examines security and performance-oriented selection and evaluation criteria for Random Number Generators (RNGs) used in cryptographic applications.
Ali Murat Garıpcan, Ebubekir Erdem
doaj   +1 more source

Author Correction: Quantum random number generators with entanglement for public randomness testing. [PDF]

Sci Rep, 2020
Jacak JE, Jacak WA, Donderowicz WA, Jacak L.   +3 more
europepmc   +1 more source