Results 111 to 120 of about 20,745 (303)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Implementation of Bayesian Network Based on Ultra-High-Speed Superconductor Random Number Generators
IEEE AccessA Bayesian network (BN) is a graphical model that represents causal relationships between events. BNs have been widely used in applications such as forecasting, diagnosis, and classification. However, analyzing large-scale BNs can lead to a computational
Rikuo Yamanaka +2 more
doaj +1 more source
Systolic random number generation for genetic algorithms
, 1996 A parallel hardware random number generator for use with a VLSI genetic algorithm (GA) processing device is proposed. The design uses a systolic array of mixed congruential random number generators. The generators are constantly reseeded with the outputs
Megson, G.M., Bland, I.M.
core
Uniform Random Number Generators [PDF]
, 1997 We briefly overview the design principles, implementation techniques, and empirical testing of uniform random number generators for simulation. We first discuss some philosophical issues and quality criteria.
Pierre L'Ecuyer
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Layered cellular automata for pseudorandom number generation
, 2007 The proposed Layered Cellular Automata (L-LCA), which comprises of a main CA with L additional layers of memory registers, has simple local interconnections and high operating speed. The time-varying L-LCA transformation at each clock can be reduced to a
Guan, SU, Tan, SK
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A Novel Design of Random Number Generators Using Chaos-Based Extremum Coding
IEEE AccessThis paper proposes a new chaos-based extremum coding method to realize a true random number generator (RNG). Based on the chain rule, we innovatively introduce two parameters into the dynamics of chaotic systems to modulate the speed and amplitude of ...
Shunsuke Araki, Ji-Han Wu, Jun-Juh Yan
doaj +1 more source
Study on Random Number Generators
, 2018 Study on Random Number Generators is the most useful task in simulation. It helps us to solve real life problems like science, gaming, simulation, lottery etc.
Anwar, Mahmuda +3 more
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