Results 141 to 150 of about 521,586 (313)
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
An Alternative Proposal for “Mixed Randomization” by Schulz and Grimes
, 2005 Summary Objective: Randomization is an important part of clinical trials. Using permuted-block randomization for forcing equal group sizes potentially harms the unpredictability of treatment assignments.
G. Kundt
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
مجله اپیدمیولوژی ایران, 2020 Background and Objectives: Clinical trials are used extensively in the compilation of systematic review studies and clinical guidelines. Critical appraisal of articles is a part of systematic review writing and also effective in citation.
Z Shateri Amiri, SS Hoseini, L Jarahi
doaj
Experimental Methods and the Welfare Evaluation of Policy Lotteries [PDF]
Policies impose lotteries of outcomes on individuals, since we never know exactly what the effects of the policy will be. In order to evaluate alternative policies, we therefore need to make some assumptions about individual preferences, even before ...
Glenn W. Harrison
core
Random Permutations, Random Sudoku Matrices and Randomized Algorithms
CoRR, 2013 Some randomized algorithms, used to obtain a random $n^2 \times n^2$ Sudoku matrix, where $n$ is a natural number, is reviewed in this study. Below is described the set $Π_n$ of all $(2n) \times n$ matrices, consisting of elements of the set $\mathbb{Z}_n =\{ 1,2,\ldots ,n\}$, such that every row is a permutation.
openaire +2 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
مجله اپیدمیولوژی ایران, 2019 Background and Objectives: Randomization is one of the principles of correct clinical trial. The aim of this study was to determine the quality of randomization in the published articles of clinical trials in the Persian-language journals indexed in ...
M Jamalian, S Kheiri
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source