Results 121 to 130 of about 1,926,046 (358)

Effectiveness of alcohol brief intervention in a general hospital: a randomized controlled trial [PDF]

, 2015
Objective: The purpose of this study was to examine the effectiveness of an alcohol brief intervention (ABI) on alcohol consumption in hazardous or harmful drinkers compared with screening alone within a general hospital setting.
Ballinger, Claire, Godwin, Jon, Howe, Tracey E., McQueen, Jean   +3 more
core   +2 more sources

Efficacy of acupuncture as an adjunctive treatment to patients with stable COPD: a multicenter, randomized, sham-controlled trial protocol

BMC Complementary Medicine and Therapies
Background Chronic obstructive pulmonary disease (COPD) is a common respiratory disease and the third leading cause of death worldwide. Previous evidence has shown that acupuncture may be an effective complementary alternative therapy for stable COPD ...
Liuyang Huang, Sha Yang, Guixing Xu, Qin Luo, Chunyan Yang, Hao Tian, Yilin Liu, Zhuo Zhou, Fengyuan Huang, Siyao Gong, Qian Li, Xin Yu, Ming Chen, Dan Huang, Yunyu Liu, Juan Tang, Ruixin Zhang, Xin Sun, Guangbing Lu, Chunfang Zeng, Shuangchun Ai, Bin Li, Jian qin Chen, Quan Luo, Chan Xiong, Zhi Zou, Qiang Hu, Xiaochao Luo, Ling Li, Mingsheng Sun, Fang Zeng, Fanrong Liang   +31 more
doaj   +1 more source

A Randomized Controlled Trial of Acetyl Salicyclic Acid in the Secondary Prevention of Mortality from Myocardial Infarction [PDF]

, 1974
P C Elwood, Alexandra Cochrane, M L Burr, P M Sweetnam, G Williams, Ellana Welsby, Samantha Hughes, Robert Renton   +7 more
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Psycho-Social Effects of Home Care: Results of a Randomized Controlled Trial [PDF]

, 1976
Lowell W. Gerson, A. F. E. BERRY
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Likelihood reweighting methods to reduce potential bias in noninferiority trials which rely on historical data to make inference

, 2013
It is generally believed that bias is minimized in well-controlled randomized clinical trials. However, bias can arise in active controlled noninferiority trials because the inference relies on a previously estimated effect size obtained from a ...
Chu, Jianxiong, Nie, Lei, Rubin, Daniel, Zhang, Zhiwei   +3 more
core   +1 more source

Acupuncture for patients with mild to moderate Alzheimer’s disease: a randomized controlled trial

BMC Complementary and Alternative Medicine, 2017
Background Alzheimer’s disease (AD) is the most common cause of dementia. However, none of medical treatment can stop or reverse the underlying neurodegenerative of AD at present.
Yujie Jia, Xuezhu Zhang, Jianchun Yu, Jingxian Han, Tao Yu, Jiangwei Shi, Lan Zhao, Kun Nie   +7 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source