Results 121 to 130 of about 4,106,658 (410)

Prognostic Adjustment with Efficient Estimators to Unbiasedly Leverage Historical Data in Randomized Trials [PDF]

arXiv, 2023
Although randomized controlled trials (RCTs) are a cornerstone of comparative effectiveness, they typically have much smaller sample size than observational studies because of financial and ethical considerations. Therefore there is interest in using plentiful historical data (either observational data or prior trials) to reduce trial sizes.
arxiv  

a randomized controlled trial [PDF]

, 2019
학위논문(석사)--서울대학교 대학원 :의과대학 의학과,2019. 8. 서정화.Introduction: During induction of general anesthesia, it is common practice to delay neuromuscular blockade until the ability to deliver mask ventilation has been confirmed, however, the benefits of this ...
임현재
core  

Effectiveness, usability, and cost-benefit of a virtual reality-based telerehabilitation program for balance recovery after stroke: a randomized controlled trial - The authors respond [PDF]

, 2015
Response to the letter "Effectiveness, Usability, and Cost-Benefit of a Virtual Reality-Based Telerehabilitation Program for Balance Recovery After Stroke: A Randomized Controlled Trial" by Lise Worthen-Chaudhari https://dx.doi.org/10.1016/j.apmr.
Alcañiz Raya, Mariano Luis, Colomer, Carolina, Llorens Rodríguez, Roberto, Noé Sebastián, Enrique   +3 more
core   +1 more source

Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial.

Journal of the American Medical Association (JAMA), 2002
CONTEXT Few depressed older adults receive effective treatment in primary care settings. OBJECTIVE To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment (IMPACT) collaborative care management program for late ...
J. Unützer, W. Katon, C. Callahan, John W. Williams, E. Hunkeler, L. Harpole, Marc Hoffing, R. D. Della Penna, P. Noël, E. Lin, P. Areán, M. Hegel, Lingqi Tang, T. Belin, S. Oishi, C. Langston   +15 more
semanticscholar   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder. [PDF]

, 2019
Objective: Selective serotonin reuptake inhibitors like sertraline have been shown in observational studies and anecdotal reports to improve language development in young children with fragile X syndrome (FXS).
Al Olaby, Reem R, Biag, Hazel Maridith B, Chen, Yanjun, Choudhary, Nimrah S, Dwyer, Patrick S, Hagerman, Randi J, Nguyen, Danh V, Potter, Laura A, Rajaratnam, Akash, Rivera, Susan M, Salcedo-Arellano, Maria J, Schneider, Andrea, Scholze, Danielle A, Tassone, Flora   +13 more
core  

Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group.

Journal of the American Medical Association (JAMA), 1999
CONTEXT Risedronate, a potent bisphosphonate, has been shown to be effective in the treatment of Paget disease of bone and other metabolic bone diseases but, to our knowledge, it has not been evaluated in the treatment of established postmenopausal ...
S. T. Harris, N. Watts, H. Genant, C. McKeever, T. Hangartner, Michael I Keller, C. Chesnut, Jacques P. Brown, E. Eriksen, M. Hoseyni, D. Axelrod, P. Miller   +11 more
semanticscholar   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Does Prophylacitc Medication Reduce Intrauterin Device (IUD) Insertion Pain in Women of Childbearing Age? [PDF]

, 2014
OBJECTIVE: The objective of this selective EBM review is to determine whether or not prophylactic medication reduces intrauterine device (IUD) insertion pain in women of childbearing age.
Deshaies, Mariel M.
core   +1 more source

Clamp-Crushing versus stapler hepatectomy for transection of the parenchyma in elective hepatic resection (CRUNSH) - A randomized controlled trial (NCT01049607) [PDF]

, 2011
Background Hepatic resection is still associated with significant morbidity. Although the period of parenchymal transection presents a crucial step during the operation, uncertainty persists regarding the optimal technique of transection.
AC Wei, Arianeb Mehrabi, C Reissfelder, CR Voyles, F Pianka, Fabian Striebel, FK Balaa, GP McEntee, Heike Elbers, Jürgen Weitz, K Takahashi, M Koch, Markus W Büchler, Moritz Koch, NN Rahbari, NN Rahbari, NN Rahbari, NN Rahbari, NN Rahbari, NN Rahbari, NN Rahbari, Nuh N Rahbari, O Jurim, P Schemmer, P Schemmer, P Schemmer, Patrick Vogler, Peter Schemmer, RT Poon, RT Poon, SG Delis, Thomas Bruckner, WR Jarnagin, Y Fong   +33 more
core   +3 more sources