Results 171 to 180 of about 1,884,582 (342)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Randomized controlled trial of a smartphone app designed to reduce unhealthy alcohol consumption

open access: yesInternet Interventions
Background and aims: Unhealthy alcohol use is common and causes tremendous harm. Most people with unhealthy alcohol use will never seek formal alcohol treatment.
John A. Cunningham   +6 more
doaj  

Randomized Controlled Trial of a Monoclonal Antibody against the Interleukin-2 Receptor (33B3.1) as Compared with Rabbit Antithymocyte Globulin for Prophylaxis against Rejection of Renal Allografts [PDF]

open access: bronze, 1990
Jean-Paul Soulillou   +7 more
openalex   +1 more source

Reflections on Randomized Control Trials [PDF]

open access: yesSocial Science & Medicine, 2018
Deaton, Angus, Cartwright, Nancy
openaire   +5 more sources

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

open access: yesFEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti   +5 more
wiley   +1 more source

A multicenter randomized controlled trial of recombinant interferon-α2b in patients with acute transfusion-associated hepatitis C [PDF]

open access: bronze, 1994
Pietro Lampertico   +6 more
openalex   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

A European multicenter randomized controlled trial of single dose surfactant therapy for idiopathic respiratory distress syndrome [PDF]

open access: bronze, 1990
Jeffrey D. Horbar   +18 more
openalex   +1 more source

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