Results 171 to 180 of about 4,106,658 (410)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

New Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini, I. Magouras, C. Chapuis‐Taillard, O. Clerc, E. Masserey, G. Peduto, O. Péter, S. Schaerrer, G. Schuepbach, G. Greub   +9 more
wiley   +1 more source

Uso Delle Medicine Complementari in Nefrologia: Una Revisione di Studi Randomizzati Controllati (RTC)

Giornale di Clinica Nefrologia e Dialisi, 2017
non disponibile (nursing)
Lisa Bovo, Francesco Burrai, Fabiola Canossa   +2 more
doaj   +1 more source

Ideal trials, target trials and actual randomized trials [PDF]

arXiv
Causal inference is the goal of randomized controlled trials and many observational studies. The first step in a formal approach to causal inference is to define the estimand of interest, and in both types of study this can be intuitively defined as the effect in an ideal trial: a hypothetical perfect randomized experiment (with representative sample ...
arxiv  

Ongoing Vaccine and Monoclonal Antibody HIV Prevention Efficacy Trials and Considerations for Sequel Efficacy Trial Designs [PDF]

arXiv, 2019
Four randomized placebo-controlled efficacy trials of a candidate vaccine or passively infused monoclonal antibody for prevention of HIV-1 infection are underway (HVTN 702 in South African men and women; HVTN 705 in sub-Saharan African women; HVTN 703/HPTN 081 in sub-Saharan African women; HVTN 704/HPTN 085 in U.S., Peruvian, Brazilian, and Swiss men ...
arxiv  

A cluster randomized controlled trial of the effectiveness and cost-effectiveness of Intermediate Care Clinics for Diabetes (ICCD) : study protocol for a randomized controlled trial [PDF]

, 2012
Background World-wide healthcare systems are faced with an epidemic of type 2 diabetes. In the United Kingdom, clinical care is primarily provided by general practitioners (GPs) rather than hospital specialists.
A Donner, A Gray, A Nocon, A Nocon, A Strauss, AG Mainous 3rd, Ainsley Hardy, Ala Szczepura, Andrew Wilson, Bazeley P, C Bradley, C Millett, C Millett, C Millett, CM Renders, Darrin Baines, EC Goyder, FE Van der Does, G Richardson, GW Welch, J Hippisley-Cox, JH Ahroni, Joseph Paul O’Hare, K Khunti, Kamlesh Khunti, KK Ray, Lambeth Diabetes Intermediate Care Team, M Campbell, MC Gulliford, MC Gulliford, Melanie Davies, MF Drummond, MM Collins, N Graves, N Papanas, Natalie Armstrong, Neil Raymond, NF Olivarius, Nigel Stallard, P Craig, P Gaede, Ponnusamy Saravanan, PW Vermunt, R Baker, R Rabin, Richard Baker, Richard Crossman, RR Holman, RR Holman, S Bellary, SJ Griffin, Sudhesh Kumar, The Euroqol Group, The NHS Confederation   +53 more
core   +3 more sources

Effects of zinc supplementation on subscales of anorexia in children: A randomized controlled trial [PDF]

, 1969
Majid Khademian, Neda Farhangpajouh, Armindokht Shahsanaee, Maryam Bahreynian, Mehran Mirshamsi, Roya Kelishadi   +5 more
openalex   +1 more source

A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

Journal of Clinical Oncology, 2004
PURPOSE Three agents with differing mechanisms of action are available for treatment of advanced colorectal cancer: fluorouracil, irinotecan, and oxaliplatin.
R. Goldberg, D. Sargent, R. Morton, C. Fuchs, R. Ramanathan, S. Williamson, B. Findlay, H. Pitot, S. Alberts   +8 more
semanticscholar   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

The design and protocol of acupuncture for migraine prophylaxis: A multicenter randomized controlled trial [PDF]

, 2009
Background: Many studies have already reported encouraging results in the prophylactic therapy of migraine by acupuncture, but there seems to be a lack of high quality randomized controlled trials from China. We design and perform a randomized controlled
A Eikermann, A Streng, CL Lam, D Irnich, D Melchart, G Bussone, GA Ulett, H Göbel, HC Diener, HC Diener, Headache Classification Subcommittee of the International Headache Society, Huilin Liu, J Alecrim-Andrade, J Sandkühler, J Yu, Jingdao Li, Jinghong Yi, JS Zhao, K Hagen, K Linde, Linpeng Wang, LP Wang, M Helene, MD Ferrari, MF Huang, Nan Li, Q Chen, S Diamond, SD Silberstein, SJ Wang, SL Hu, SS Holcomb, SY Yu, T Lundeberg, Y Zhao, Yan Zhang, YJ Luo, YL Lo   +37 more
core   +2 more sources