Results 21 to 30 of about 4,106,658 (410)

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial.

Journal of the American Medical Association (JAMA), 2002
CONTEXT Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain.
J. Rossouw, G. Anderson, Ross L. Prentice, Andrea Z LaCroix, C. Kooperberg, M. L. Stefanick, R. Jackson, Shirley A A Beresford, Barbara V. Howard, Karen C. Johnson, J. Kotchen, Judith Ockene   +11 more
semanticscholar   +1 more source

Randomized controlled trials [PDF]

Journal of British Surgery, 1994
Definition The radial arm maze, originally developed by David Olton, is an apparatus that taps into natural foraging abilities of rodents and can be used to test different types of memory, including short-term (working), longterm (reference), nonspatial and spatial memory.
J. R. Farndon, J. A. Murie, C. D. Johnson, R. C. N. Williamson, J. J. Earnshaw   +4 more
openaire   +1 more source

Dermatology and Randomized Control Trials

Indian Dermatology Online Journal, 2021
Well-designed and rigorously conducted randomized controlled trial (RCT) can produce most valid and precise scientific evidence. Any intervention, be it systemic or topical medicine, dermatology procedure needs to be tested for its efficacy in improving particular disease condition and RCT should come into mind of investigator.
Amrita Sil, Nayankumar Harshadkumar Patel   +1 more
openaire   +3 more sources

Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.

New England Journal of Medicine, 2020
BACKGROUND In adults with active lupus nephritis, the efficacy and safety of intravenous belimumab as compared with placebo, when added to standard therapy (mycophenolate mofetil or cyclophosphamide-azathioprine), are unknown.
R. Furie, B. Rovin, F. Houssiau, A. Malvar, Y. Teng, G. Contreras, Z. Amoura, Xueqing Yu, C. Mok, M. Santiago, A. Saxena, Y. Green, B. Ji, C. Kleoudis, S. Burriss, Carly Barnett, D. Roth   +16 more
semanticscholar   +1 more source

Extraction socket preservation using porcine-derived collagen membrane alone or associated with porcine-derived bone. Clinical results of randomized controlled study [PDF]

, 2017
The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous ...
De Angelis, Francesca, Di Carlo, Stefano, Guarnieri, Renzo, Mencio, Francesca, Pompa, Giorgio, Stefanelli, Luigi   +5 more
core   +2 more sources

Long-term Randomized Controlled Trial [PDF]

, 2022
Funding Information: The authors thank Sarah E Scott for her valuable contributions as the trial manager and in the user experience evaluation, and Susana Cunha for her contribution in conducting and reporting the focus groups.
Bundgaard, Lise, Duarte, Cristiana, Dunning, Alice, Encantado, Jorge, Ermes, Miikka, Hansen, Susanne, Harjumaa, Marja, Heitmann, Berit Lilienthal, Horgan, Graham, James Stubbs, R., Larsen, Sofus C., Lähteenmäki, Liisa, Marques, Marta M., Matos, Marcela, Mattila, Elina, O'Driscoll, Ruairi, Palmeira, António L., Ramsey, Lauren, Santos, Inês, Silva, Marlene N., Turicchi, Jake   +20 more
core   +5 more sources

A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics.

New England Journal of Medicine, 2019
BACKGROUND Although several experimental therapeutics for Ebola virus disease (EVD) have been developed, the safety and efficacy of the most promising therapies need to be assessed in the context of a randomized, controlled trial.
S. Mulangu, L. Dodd, R. Davey, Olivier Tshiani Mbaya, M. Proschan, Daniel Mukadi, Mariano Lusakibanza Manzo, Didier Nzolo, Antoine Tshomba Oloma, A. Ibanda, Rosine Ali, Sinaré Coulibaly, A. Levine, R. Grais, Janet Diaz, H. Lane, J. Muyembe-Tamfum, Billy Sivahera, Modet Camara, R. Kojan, R. Walker, Bonnie Dighero-kemp, H. Cao, Philippe Mukumbayi, Placide Mbala-Kingebeni, Steve Ahuka, S. Albert, Tyler Bonnett, Ian Crozier, Michael Duvenhage, C. Proffitt, M. Teitelbaum, T. Moench, J. Aboulhab, K. Barrett, Kelly Cahill, Katherine Cone, R. Eckes, L. Hensley, B. Herpin, E. Higgs, J. Ledgerwood, J. Pierson, M. Smolskis, Ydrissa Sow, J. Tierney, S. Sivapalasingam, W. Holman, Nikki Gettinger, D. Vallée, J. Nordwall   +50 more
semanticscholar   +1 more source

Interpreting Randomized Controlled Trials

Cancers, 2023
This article describes rationales and limitations for making inferences based on data from randomized controlled trials (RCTs). We argue that obtaining a representative random sample from a patient population is impossible for a clinical trial because patients are accrued sequentially over time and thus comprise a convenience sample, subject only to ...
Pavlos Msaouel, Juhee Lee, Peter F Thall
openaire   +2 more sources

Optimal allocation strategies in platform trials [PDF]

Statistical Methods in Medical Research, 2024, 2023
Platform trials are randomized clinical trials that allow simultaneous comparison of multiple interventions, usually against a common control. Arms to test experimental interventions may enter and leave the platform over time. This implies that the number of experimental intervention arms in the trial may change over time.
arxiv   +1 more source

Clinical and radiographic evaluation of a new stain-free tricalcium silicate cement in pulpotomies [PDF]

Brazilian Oral Research, 2020
The aim of this study was to evaluate and compare the clinical and radiographic success rates of pulpotomies in primary molars using a new stain-free tricalcium silicate cement (Bio-C Pulpo) versus a conventional white MTA (MTA Angelus) as a pulpotomy ...
Suéllen Priscilla Rodrigues de LIMA, Greissy Lopes dos SANTOS, Antonio FERELLE, Solange de Paula RAMOS, Juliano Pelim PESSAN, Cássia Cilene DEZAN-GARBELINI   +5 more
doaj   +1 more source