Results 21 to 30 of about 4,120,157 (359)

Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

Journal of Psychopharmacology, 2016
Background: Clinically significant anxiety and depression are common in patients with cancer, and are associated with poor psychiatric and medical outcomes. Historical and recent research suggests a role for psilocybin to treat cancer-related anxiety and
Stephen Ross, Anthony P. Bossis, Jeffrey R. Guss, Gabrielle Agin-Liebes, T. Malone, Barry H Cohen, S. Mennenga, Alexander B. Belser, K. Kalliontzi, J. Babb, Zhe Su, P. Corby, B. Schmidt   +12 more
semanticscholar   +1 more source

A Randomized, Controlled Trial of Liraglutide for Adolescents with Obesity.

New England Journal of Medicine, 2020
BACKGROUND Obesity is a chronic disease with limited treatment options in pediatric patients. Liraglutide may be useful for weight management in adolescents with obesity.
A. Kelly, P. Auerbach, M. Barrientos-Pérez, I. Gies, P. M. Hale, C. Marcus, L. Mastrandrea, Nandana Prabhu, S. Arslanian   +8 more
semanticscholar   +1 more source

Extraction socket preservation using porcine-derived collagen membrane alone or associated with porcine-derived bone. Clinical results of randomized controlled study [PDF]

, 2017
The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous ...
De Angelis, Francesca, Di Carlo, Stefano, Guarnieri, Renzo, Mencio, Francesca, Pompa, Giorgio, Stefanelli, Luigi   +5 more
core   +2 more sources

Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia

JCSM Rapid Communications, 2022
Background Cancer cachexia (CC) impacts quality of life, physical function, anticancer treatment response, and survival. Inflammation is a prominent pathomechanism of CC.
David Blum, Caroline Hertler, Rolf Oberholzer, Susanne deWolf‐Linder, Markus Joerger, Christoph Driessen, Florian Strasser   +6 more
doaj   +1 more source

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]

, 2012
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat, AM Cheung, C Brun-Buisson, C Rossi, Cecilia M O’Kane, Christine McNally, Daniel F McAuley, DJ Kor, Excellence NIfHaC, F Gao Smith, Gavin D Perkins, GD Rubenfeld, GR Bernard, Grainne Crealey, Irish Critical Care Trials Group, John G Laffey, KF Schulz, LA Curtis, Lynn Murphy, M Shyamsundar, MA Matthay, Mark Cross, Michael Stevenson, MS Herridge, RG Brower, S Harvey, SE Erickson, T Craig, The ARDS Network investigators, The EuroQol Group, TR Craig, TW Felton   +31 more
core   +1 more source

Malaria positivity following a single oral dose of azithromycin among children in Burkina Faso: a randomized controlled trial

BMC Infectious Diseases, 2022
Background Azithromycin is a broad-spectrum antibiotic that has moderate antimalarial activity and has been shown to reduce all-cause mortality when biannually administered to children under five in high mortality settings in sub-Saharan Africa.
Jessica Brogdon, Clarisse Dah, Ali Sié, Mamadou Bountogo, Boubacar Coulibaly, Idrissa Kouanda, Mamadou Ouattara, Guillaume Compaoré, Eric Nebie, Mariam Seynou, Elodie Lebas, Fanice Nyatigo, Huiyu Hu, Benjamin F. Arnold, Thomas M. Lietman, Catherine E. Oldenburg   +15 more
doaj   +1 more source

Acupuncture randomized trials (ART) in patients with chronic low back pain and osteoarthritis of the knee - Design and protocols [PDF]

, 2003
Background: We report on the study design and protocols of two randomized controlled trials (Acupuncture Randomized Trials = ART) that investigate the efficacy of acupuncture in the treatment of chronic low back pain and osteoarthritis of the knee ...
Becker-Witt, C., Brinkhaus, Benno, Hummelsberger, J., Irnich, D., Jena, S., Linde, K., Melchart, Dieter, Streng, A., Wagenpfeil, S., Willich, S. N.   +9 more
core   +1 more source

Intraoperative and postoperative clinical evaluation of the hysteroscopic morcellator system for endometrial polypectomy: A prospective, randomized, single-blind, parallel group comparison study

Gynecology and Minimally Invasive Therapy, 2018
Objective: To evaluate the TRUCLEAR™ system (Smith and Nephew Inc., London, UK), a hysteroscopic system that morcellates and aspirates masses, in terms of the operating time, surgeon's convenience, and effect on patients compared with conventional ...
Akira Tsuchiya, Yasunori Komatsu, Reiko Matsuyama, Hiroko Tsuchiya, Yuri Takemura, Osamu Nishii   +5 more
doaj   +1 more source

Improving end-of-life care in acute geriatric hospital wards using the Care Programme for the Last Days of Life : study protocol for a phase 3 cluster randomized controlled trial [PDF]

, 2015
Background: The Care Programme for the Last Days of Life has been developed to improve the quality of end-of-life care in acute geriatric hospital wards.
Cohen, Joachim, Costantini, Massimo, Deliens, Luc, Smets, Tinne, Van Den Noortgate, Nele, Verhofstede, Rebecca   +5 more
core   +2 more sources

Necessity of pharyngeal anesthesia during transoral gastrointestinal endoscopy: a randomized clinical trial [PDF]

Clinical Endoscopy, 2023
Background/Aims The necessity for pharyngeal anesthesia during upper gastrointestinal endoscopy is controversial. This study aimed to compare the observation ability with and without pharyngeal anesthesia under midazolam sedation.
Tomoyuki Hayashi, Yoshiro Asahina, Yasuhito Takeda, Masaki Miyazawa, Hajime Takatori, Hidenori Kido, Jun Seishima, Noriho Iida, Kazuya Kitamura, Takeshi Terashima, Sakae Miyagi, Tadashi Toyama, Eishiro Mizukoshi, Taro Yamashita   +13 more
doaj   +1 more source