Results 71 to 80 of about 3,612,030 (344)
Do antiarrhythmics prevent sudden death in patients with heart failure? [PDF]
, 2003 Beta-blockers (class II antiarrhythmics) reduce sudden death and total mortality in patients with heart failure (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials).
Ball, Thomas A. +2 more
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Appetite suppressants and valvular heart disease - a systematic review [PDF]
, 2002 Background Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain.
AJ Burger +28 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Stratification Trees for Adaptive Randomization in Randomized Controlled Trials
, 2020 This paper proposes an adaptive randomization procedure for two-stage randomized controlled trials. The method uses data from a first-wave experiment in order to determine how to stratify in a second wave of the experiment, where the objective is to ...
Tabord-Meehan, Max
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From wealth to health: evaluating microfinance as a complex intervention [PDF]
, 2017 Innovative interventions that address the social determinants of health are required to help reduce persistent health inequalities. We argue that microcredit can act in this way and develop a conceptual framework from which to examine this.
Biosca , Olga +2 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
Randomization in randomized clinical trials: From theory to practice
حیات, 2016 Background & Aim: Randomized clinical trials (RCTs) are studies which are able to provide the most valid evidence to compare various interventions in health research.
Mina Mohammady, Leila Janani
doaj
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Boosting the Life Chances of Young Men of Color: Evidence From Promising Programs [PDF]
, 2014 In light of the momentum building to improve the fortunes of young men of color, this review examines what is known about this population -- particularly related to their struggles in the labor market -- and highlights programs that are shown by ...
Christopher Wimer, Dan Bloom
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source