Results 11 to 20 of about 1,792,348 (283)
Investigator-initiated versus industry-sponsored trials – visibility and relevance of randomized controlled trials in clinical practice guidelines (IMPACT) [PDF]
BMC Medical Research MethodologyBackground The goal of evidence-based medicine is to make clinical decisions based on the best available, relevant evidence. For this to be possible, studies such as randomized controlled trials (RCTs), which are widely considered to provide the best ...
Manuel Hecht +4 more
doaj +2 more sources
What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]
São Paulo Medical Journal, 2023 BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco +2 more
doaj +1 more source
Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction – a narrative review [PDF]
International Brazilian Journal of Urology, 2023 Objectives: To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
Rodrigo R. Vieiralves +2 more
doaj +1 more source
Celecoxib for Mood Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Journal of Clinical Medicine, 2023 The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory parameters have not yet been comprehensively evaluated. The aim of this study was to systematically summarize the available knowledge on this topic.
Adam Gędek +4 more
semanticscholar +1 more source
Nutrients, 2022 Magnesium (Mg) may have several beneficial effects on human health outcomes. One hypothesized mechanism eliciting such effects is the action of Mg on serum inflammatory parameters. However, studies on this topic to date have several important limitations.
N. Veronese +4 more
semanticscholar +1 more source
Perspectives in Clinical Research, 2022 Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan +2 more
doaj +1 more source
Nutrients, 2022 β-carotene is widely available in plant-based foods, while the efficacy of β-carotene supplementation on cardiovascular disease (CVD) risk remains controversial. Hence, we performed a systematic review and meta-analysis on randomized controlled trials to
Jiaqi Yang, Yulin Zhang, X. Na, A. Zhao
semanticscholar +1 more source
The effect FRIENDS program on the anxiety of adolescent girls
Social Determinants of Health, 2021 Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer +3 more
doaj +1 more source
Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study [PDF]
The Korean Journal of Internal Medicine, 2022 Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Eileen L. Yoon +13 more
doaj +1 more source
Journal of Youth and Adolescence, 2022 Past meta-analyses in mental health interventions failed to use stringent inclusion criteria and diverse moderators, therefore, there is a need to employ more rigorous methods to provide evidence-based and updated results on this topic.
Qiyang Zhang +2 more
semanticscholar +1 more source