Results 11 to 20 of about 313,863 (333)

Citation classics in systematic reviews and meta-analyses : who wrote the top 100 most cited articles? [PDF]

, 2013
Background: Systematic reviews of the literature occupy the highest position in currently proposed hierarchies of evidence. The aims of this study were to assess whether citation classics exist in published systematic review and meta-analysis (SRM ...
Clarke, Aileen, Okwundu, Charles I., Uthman, Olalekan A., Wiysonge, Charles S., Young, Taryn   +4 more
core   +15 more sources

Equivalence trials

Perspectives in Clinical Research, 2022
In an equivalence trial, researchers aim to show that a new intervention is more or less similar to an existing standard of care, i.e., the two are “equivalent”.
Priya Ranganathan, C S Pramesh, Rakesh Aggarwal   +2 more
doaj   +1 more source

Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study [PDF]

The Korean Journal of Internal Medicine, 2022
Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Eileen L. Yoon, Sang Bong Ahn, Dae Won Jun, Yong Kyun Cho, Do Seon Song, Jae Yoon Jeong, Hee Yeon Kim, Young Kul Jung, Myeong Jun Song, Sung Eun Kim, Hyoung Su Kim, Soung Won Jeong, Sang Gyune Kim, Tae Hee Lee   +13 more
doaj   +1 more source

Topical vitamin D3: A randomized controlled trial (RCT) [PDF]

Clinical Nutrition ESPEN, 2018
The intent of this study was to test the effect of Top-D, a topical Vitamin D preparation, in delivering vitamin D.Five hundred and fifty healthy patients, with vitamin D insufficiency and deficiency were recruited after written informed consent. Demographic data was recorded, adequate history and clinical examination was done to rule out any metabolic
Dakheel A. Al-Dakheel, Dalal A. Bubshait, Dalal A. Bubshait, Fawaz M AlAnii   +3 more
openaire   +3 more sources

Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial [PDF]

Anesthesia Progress, 2019
This study aims to compare the effect of topical anesthesia against the use of no topical agent on pain of needle penetration and local anesthesia deposition during buccal infiltration in anterior maxilla. In a randomized controlled trial, 100 adult participants were randomly allocated to the benzocaine group (received 20% benzocaine gel) and no ...
Nurain Rehman, Samir Riaz Qazi
openaire   +3 more sources

Topical Endoxifen for Mammographic Density Reduction—A Randomized Controlled Trial

The Oncologist, 2022
Abstract Although breast cancer incidence is increasing, there are few primary preventive initiatives. Tamoxifen can reduce breast cancer incidence but is rarely used for primary prevention due to adverse events and tolerance issues. We tested if endoxifen, a tamoxifen metabolite, applied directly to the skin of the breast, could reduce ...
Magnus Bäcklund, Mikael Eriksson, Marike Gabrielson, Mattias Hammarström, Steve Quay, Jenny Bergqvist, Roxanna Hellgren, Kamila Czene, Per Hall   +8 more
openaire   +2 more sources

Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials

International Journal of Women’s Dermatology, 2022
Background:Aging, an inevitable and continuous process in one’s lifetime, has all along been a focus of interest, especially for women, yet photoaging treatment to slow the process remains challenging. Recent studies have demonstrated the potency of topical tretinoin in the treatment of photoaging.
Irma Bernadette S. Sitohang, MD, PhD, Wresti Indriatmi Makes, MD, PhD, Normalina Sandora, MD, PhD, Jose Suryanegara, MD   +3 more
openaire   +3 more sources

Interventions in hypertension: systematic review and meta-analysis of natural and quasi-experiments

Clinical Hypertension, 2022
Background Hypertension is an urgent public health problem. Consistent summary from natural and quasi-experiments employed to evaluate interventions that aim at preventing or controlling hypertension is lacking in the current literature.
Tong Xia, Fan Zhao, Roch A. Nianogo
doaj   +1 more source

Visual data: a new tool to improve the presentation of clinical trial results

Einstein (São Paulo), 2019
Randomized controlled trials are known to be the best tool to determine the effects of an intervention; however, most healthcare professionals are not able to adequately understand the results.
Raphael Mendes Ritti-Dias, Marilia de Almeida Correia, Breno Quintella Farah   +2 more
doaj   +2 more sources

Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy [PDF]

Pain, 2012
A length-dependent neuropathy with pain in the feet is a common complication of diabetes (painful diabetic neuropathy). It was hypothesized that pain may arise from sensitized-hyperactive cutaneous nociceptors, and that this abnormal signaling may be reduced by topical administration of the α(2)-adrenergic agonist, clonidine, to the painful area.
Claudia M. Campbell, Kerrie L. Brady, Mark S. Kipnes, Margaret Kelly, William K. Schmidt, Bruce C. Stouch, James N. Campbell, Karin L. Petersen, Karin L. Petersen, Michael C. Rowbotham, Michael C. Rowbotham   +10 more
openaire   +4 more sources