Results 71 to 80 of about 3,329 (143)

Understanding RanGTP dependent microtubule assembly : Idenification of DnaJB6 as a RanGTP regulated factor involved in microtubule organization during mitosis

Three microtubule (MT) assembly pathways participate in the assembly of the bipolar spindle: the centrosomal pathway, the augmin dependent amplification pathway and the RanGTP/chromosome dependent pathway. To form the spindle, all these MTs are organized
Rosas Salvans, Miquel
core  

Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells

, 2011
We have previously reported that G-actin accumulation in nuclei is a universal phenomenon of cellular senescence. By employing primary culture of human diploid fibroblast (HDF) and stress-induced premature senescence (SIPS), we explored whether the ...
Su Hyun Park, Tae Jun Park, In Kyoung Lim, Park, SH, Lim, IK, Park, TJ   +5 more
core   +1 more source

Identifizierung und Charakterisierung eines neuen RanGTP-bindenden Proteins in der Hefe Saccharomyces cerevisiae

, 2002
Der kleinen GTPase Ran kommt in interphasischen Zellen eine zentrale Rolle beim Transport von Molekülen durch die Kernmembran zu.In höheren eukary- ontischen Zellen zerfällt während der Prometaphase der Mitose die Kern- membran.Es konnte neuerdings ...
Braunwarth, Andreas Benedict
core   +1 more source

The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes.

, 2015
The inner nuclear membrane (INM) protein Nemp1/TMEM194A has previously been suggested to be involved in eye development in Xenopus, and contains two evolutionarily conserved sequences in the transmembrane domains (TMs) and the C-terminal region, named ...
Fumihiko Hakuno, Hiroshi Mamada (735469), Masanori Taira, Takashi Shibano (735468), Shibano Takashi, Takahashi Shin-Ichiro, Masanori Taira (735470), Fumihiko Hakuno (202707), Mamada Hiroshi, Shin-Ichiro Takahashi, Hakuno Fumihiko, Hiroshi Mamada, Taira Masanori, Takashi Shibano, Shin-Ichiro Takahashi (202755)   +14 more
core   +1 more source

Illustration of CFDP1 function in ensuring structural stability of centromeric heterochromatin and its effect on RCC1-mediated generation of RanGTP levels.

(A) CFDP1 binds to minor and major satellite heterochromatin and stabilizes a condensed chromatin architecture featuring normal H2A.Z chromatin levels and HP1α binding to H3K9me3 histone modifications. Chromatin bound RCC1 maintains high levels of RanGTP
Qian Xu (119888), Xianghong Luan (255495), Gokul Gopinathan (7930679), Thomas G. H. Diekwisch (7469093)   +3 more
core   +1 more source

Interaction of region B with RanGTP.

, 2015
A. Yeast two hybrid screening. Left panel, schematic representation of the bait, the Bt region of Mm_Nemp1 (DBD-Mm_Bt). Right panels, colony formation (in duplicate) of yeast AH109 cells transformed with DBD (upper) or DBD-Mm_Bt (lower) with AD-Mm_Ran on
Hiroshi Mamada (735469), Takashi Shibano (735468), Shin-Ichiro Takahashi (202755), Masanori Taira (735470), Fumihiko Hakuno (202707)   +4 more
core   +1 more source

Role of RanGTP and spindle assembly factors in cilia assembly and function

El cilio primario es una estructura formada por microtúbulos que sobresale de la superficie celular durante G0 teniendo una función de orgánulo sensor.
Mòdol Cano, Aitor
core  

Origin of the nucleus and Ran-dependent transport to safeguard ribosome biogenesis in a chimeric cell-1

, 2011
. (B) Steady state distribution of RanGTP, RanGDP, karyopherin and karyopherin-RanGTP along the line shown in panel (A). (C) Steady state distribution of host-RP, mitochondrial-RP, karyopherin-host-RP and karyopherin-mitochondrial-RP complexes along the ...
Gáspár Jékely (86311)
core   +1 more source

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding. [PDF]

J Biol Chem
Keplinger AJ, Srinivasan PA, Christensen SM, Suarez C, Ruthenburg AJ.   +4 more
europepmc   +1 more source

RNA export through the nuclear pore complex: pathways, mechanisms, and imaging strategies. [PDF]

RNA Biol
Fu D, Yu W, Zhang F, Rush C, Tingey M, Yang W.   +5 more
europepmc   +1 more source