Ranitidine Alleviates Anxiety-like Behaviors and Improves the Density of Pyramidal Neurons upon Deactivation of Microglia in the CA3 Region of the Hippocampus in a Cysteamine HCl-Induced Mouse Model of Gastrointestinal Disorder [PDF]
Brain Sciences, 2023 Elevated levels of histamine cause over-secretion of gastric hydrochloric acid (HCl), leading to gastrointestinal (GI) disorders and anxiety. Ranitidine is an antihistamine drug widely used in the management of GI disorders, as it works by blocking the ...
Divya Bharathi Selvaraj +3 more
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Developing a Chitosan/polyvinyl alcohol hydrogel for gastro-retentive release of ranitidine and enhanced anti-ulcerative properties [PDF]
BMC BiotechnologyRanitidine is widely used to treat gastrointestinal conditions, but recent studies have revealed severe potential side effects, including a link to cancer.
Shimaa A. Sadek +13 more
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Genotoxic effects of NDMA-contaminated ranitidine on Allium cepa cells and unveiling carcinogenic mechanisms via DFT and molecular dynamics simulation study [PDF]
Scientific ReportsThis study investigated the potential genotoxic and carcinogenic effects of N-nitrosodimethylamine (NDMA), a hazardous compound found in ranitidine formulations that are used to treat excessive stomach acid.
Mst. Kusum Kaly +4 more
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Premedication in pediatric Meckel scintigraphy: pantoprazole versus ranitidine for optimizing scan quality. [PDF]
Pediatr RadiolÖnner H +6 more
europepmc +3 more sources
Pakistan Armed Forces Medical Journal, 2021 Objective: To explore the prokinetic effect of Ranitidine, to compare it with the prokinetic effect of Neostigmine and to observe the potentiating prokinetic effect of Ranitidine and Neostigmine in combination.
Aroosa Ishtiaq Butt +4 more
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Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine. [PDF]
PLoS ONE, 2017 Ranitidine (Zantac®) is a H2-receptor antagonist commonly used for the treatment of acid-related gastrointestinal diseases. Ranitidine was reported to be a substrate of the organic cation transporters OCT1 and OCT2. The hepatic transporter OCT1 is highly
Marleen Julia Meyer +3 more
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The Study of Ranitidine Interference With Morphine Detection Test by Thin-Layer Chromatography [PDF]
Avicenna Journal of Medical Biochemistry, 2018 Background: Drug abuse is a global and critical problem. One of the most frequent practices done in order to detect the drugs of abuse is Urine Drug Screen. However, for changing the drug test results, adulterants and urine substitutes are being designed.
Amir Miri +3 more
doaj +1 more source
Association between ranitidine use with potential NDMA impurities and risk of cancer in Korea
Scientific Reports, 2022 N-Nitrosodimethylamine (NDMA) detected above the acceptable level in ranitidine products has been a great global concern. To examine the risk of cancer among people treated with ranitidine, we conducted a cohort study using the National Health Insurance ...
Kyung-In Joung +4 more
doaj +1 more source
Pharmaceuticals, 2023 Background: Histamine H2 receptor antagonists are a group of drugs that inhibit gastric juice secretion in gastrointestinal diseases. However, there is evidence to suggest that H2 blockers have a broader spectrum of activity.
Grzegorz Biedrzycki +6 more
doaj +1 more source
PLoS ONE, 2022 Polypharmacy may be considered as the customary practice to provide optimum care services to patients but inter resulted in augmented probability of multiple drug interaction. Keeping in view the importance of drug interaction possibility, this study was
Shaheen Perveen +5 more
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