Results 31 to 40 of about 28,458 (210)

Medicine and Media: The Ranitidine Debate

Clinical and Translational Science, 2020
Ranitidine has been the topic of recent media reports. Current findings, confirmed by the US Food and Drug Administration, indicate that some ranitidine products contain a substance that may be carcinogenic.
Jennifer A. Wagner, Jennifer M. Colombo
doaj   +1 more source

Bismuth coordination networks containing deferiprone: synthesis, characterisation, stability and antibacterial activity [PDF]

, 2015
A series of bismuth–dicarboxylate–deferiprone coordination networks have been prepared and structurally characterised. The new compounds have been demonstrated to release the iron overload drug deferiprone on treatment with PBS and have also been shown ...
An, Andrew D. Burrows, Andrews, Bland, Burrows, Furukawa, Gavin W. Roffe, Ge, Ge, Henry J. Windle, Horcajada, Janiak, John Spencer, Li, Lin, Lou, Mary F. Mahon, Miller, Monika Jurcic, Sandrine Pierrat, Schindler, Sox, Su, Tamames-Tabar, Thirumurugan, Thirumurugan, Thompson, Wibowo, Yang   +28 more
core   +2 more sources

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Effect of an antiandrogenic H2 receptor antagonist on hepatic regeneration in rats [PDF]

, 1988
Because biochemical 'feminization' of the liver in males is observed with hepatic regeneration and because the hepatic regenerative response in females is greater than that in males, the posibility that antiandrogens might potentiate liver regeneration ...
Chapchap, P, Eagon, PK, Kahn, D, Makowka, L, Podesta, L, Starzl, TE, Svanas, GW, Van Thiel, DH   +7 more
core  

Drug Hepatotoxicity: Environmental Factors [PDF]

, 2017
Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

PM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy, Joshua C. Wiener, Karen Pratt, Laura Brunton   +3 more
wiley   +1 more source

Long‐term outcomes of gastric bypass surgery in two Lusitano foals: Contemporary evidence for surgical decision‐making

Equine Veterinary Education, EarlyView.
Summary Gastric outflow obstruction (GOO) occasionally requires surgical intervention in foals when medical management fails. Current literature lacks consensus on several surgical decisions, with most comprehensive reports dating back over a decade. Critical aspects—including jejunal loop orientation and necessity of jejunojejunostomy—remain debated ...
P. Fernández Hernández, M. Valero González, F. Bulnes Jiménez, N. Venegas Chávez, B. Fuentes Romero, M. Iglesias García, J. Jiménez Fragoso, M. Martín Cuervo, L. J. Ezquerra Calvo   +8 more
wiley   +1 more source

Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

Periodontology 2000, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin, Troy B. Tran, Paras Ahmad, Nima Farshidfar, Georgios E. Romanos, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Biochemical disturbances caused by ranitidine in rats: attention to bilirubin–lipids relation and benefits of capsiate

Future Journal of Pharmaceutical Sciences
Ranitidine is an H2-receptor antagonist used to control acid disorders in the gastrointestinal tract. But the long-term use of ranitidine is related to liver dysfunction, which may alter bilirubin levels and disrupt lipid metabolism.
Nawal Z. Haggag, Nora E. M. Shaheen, Amal A. Shahin, Eman S. Elhadidi, Eman A. Sherif   +4 more
doaj   +1 more source

ADMINISTRATION OF H2 BLOCKERS IN NSAID INDUCED GASTROPATHY IN RATS: effect on histopathological changes in gastric, hepatic and renal tissues

Arquivos de Gastroenterologia
Background Nonsteroidal anti-inflammatory drugs induces gastric mucosal lesions because of its acidic properties. Ranitidine, an H2 receptor antagonist, has proved beneficial in patients with gastric ulcers.
Sachin MANOCHA, Dushyant LAL, Subramanian VENKATARAMAN   +2 more
doaj   +1 more source