Results 41 to 50 of about 12,942 (170)

Population Pharmacokinetic and Exposure‐Response Analysis of Vancomycin Nephrotoxicity in Cystic Fibrosis Patients

open access: yesPediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Introduction Acute pulmonary exacerbations (APE) in persons with cystic fibrosis (PwCF) are associated with a reduction in long‐term pulmonary function. Vancomycin is recommended as first‐line treatment of methicillin‐resistant Staphylococcus aureus ‐APE in PwCF.
Jessica Barry   +7 more
wiley   +1 more source

Medicine and Media: The Ranitidine Debate

open access: yesClinical and Translational Science, 2020
Ranitidine has been the topic of recent media reports. Current findings, confirmed by the US Food and Drug Administration, indicate that some ranitidine products contain a substance that may be carcinogenic.
Jennifer A. Wagner, Jennifer M. Colombo
doaj   +1 more source

Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling. ABSTRACT pH‐dependent drug–drug interactions (DDIs) commonly occur when acid‐reducing agents (ARAs) are co‐administered with weakly basic drugs.
Yuanfang Qin   +6 more
wiley   +1 more source

Pufferfish exposure and presumed tetrodotoxicosis in Australian dogs: 372 cases (2007–2018)

open access: yesAustralian Veterinary Journal, Volume 104, Issue 8, Page 497-508, August 2026.
Introduction Tetrodotoxin (TTX) is a neurotoxin found in pufferfish that results in the blockade of excitatory conduction and clinical signs including gastrointestinal upset and paralysis. The objectives of this study were to describe the epidemiology of pufferfish exposure and presumed tetrodotoxicosis in dogs, and to determine associations with the ...
J Hanson, CR Sharp, EM Leister
wiley   +1 more source

Long‐term outcomes of gastric bypass surgery in two Lusitano foals: Contemporary evidence for surgical decision‐making

open access: yesEquine Veterinary Education, Volume 38, Issue 8, Page e509-e515, August 2026.
Summary Gastric outflow obstruction (GOO) occasionally requires surgical intervention in foals when medical management fails. Current literature lacks consensus on several surgical decisions, with most comprehensive reports dating back over a decade. Critical aspects—including jejunal loop orientation and necessity of jejunojejunostomy—remain debated ...
P. Fernández Hernández   +8 more
wiley   +1 more source

Intravenous Bolus versus Continuous Infusion of Famotidine or Ranitidine on 24 H Intragastric Acidity in Fasting Healthy Volunteers

open access: yesCanadian Journal of Gastroenterology, 1995
Infusions of H2-receptor antagonists may be clinically indicated to maintain intragastric pH above 4 to reduce acute gastric mucosal lesions or to treat patients with bleeding peptic ulcers.
ABR Thomson   +4 more
doaj   +1 more source

A New Method for Exploring the Early Stages of the Crystallization of Small Organic Carboxylic Acids at Constant pH and Temperature and Quantitatively Assessing Additive Effects

open access: yesChemistry–Methods, Volume 6, Issue 7, July 2026.
We introduce a titration‐based method to explore the early stages of the crystallization of small organic molecules with carboxylic acid functions in water. It enables the determination of fundamental physicochemical characteristics (pKa values and solubilities) and the quantitative study of prenucleation, nucleation, and early postnucleation stages ...
Felix Lücke   +2 more
wiley   +1 more source

PENGARUH PEMBERIAN RANITIDINE TERHADAP SPERMATOGENESIS TIKUS Wistar DENGAN INTOKSIKASI METANOL AKUT DILIHAT SECARA HISTOPATOLOGIS

open access: yesJurnal Kedokteran Diponegoro, 2017
Latar belakang: Metanol memiliki efek toksik melalui metabolitnya yaitu asam format yang mengakibatkan gangguan spermatogenesis. Ranitidine mempunyai enzim yang dapat menghambat terbentuknya metabolit asam format sehingga diharapkan akan mengurangi efek ...
James Otniel   +2 more
doaj   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman   +6 more
wiley   +1 more source

The Associations Between Acid‐Suppressive Drug Intake and Symptom Profiles in Functional Dyspepsia Patients Referred for Open‐Access Endoscopy

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 6, July 2026.
ABSTRACT Background Functional dyspepsia (FD) is characterised by postprandial fullness, early satiation, epigastric pain, or burning without structural abnormalities on upper endoscopy. Proton pump inhibitors (PPIs) are the preferred first‐line therapy.
Scheepers Janne   +4 more
wiley   +1 more source

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