Results 241 to 250 of about 1,084,074 (266)

Detection and characterization of RANK ligand and osteoprotegerin in the thyroid gland

Journal of Cellular Biochemistry, 2002
AbstractReceptor activator of NF‐κB (RANK) ligand (RANKL) and osteoprotegerin (OPG) play essential roles in bone metabolism and immune responses. RANKL activates RANK, which is expressed by osteoclasts and dendritic cells (DC), whereas OPG acts as its decoy receptor. The role of RANKL and OPG in thyroid physiology is unclear. Northern analysis revealed
Lorenz C, Hofbauer, Sibylle, Kluger, Christian A, Kühne, Colin R, Dunstan, Andreas, Burchert, Michael, Schoppet, Andreas, Zielke, Armin E, Heufelder   +7 more
openaire   +2 more sources

RANK ligand is a prerequisite for cancer‐associated osteolytic lesions

The Journal of Pathology, 2002
AbstractBreast cancer is frequently associated with osteolytic bone metastasis, where osteoclasts play a major role in bone destruction. Recently, osteoclast differentiation factor (RANKL) has been identified as a prerequisite for the formation and maintenance of osteoclasts from haematopoietic precursors.
Sohei, Kitazawa, Riko, Kitazawa
openaire   +2 more sources

TNF‐α expression is transcriptionally regulated by RANK ligand

Journal of Cellular Physiology, 2004
AbstractTumor necrosis factor (TNF)‐α is known for its osteoclastogenic and resorptive activities. Induction of osteoclastogenesis by receptor activator of NF‐κB ligand (RANKL) is accompanied by increased TNF‐α expression. In the present study we investigated the mechanism by which RANKL induces expression of TNF‐α in osteoclast precursors.
W, Zou, A, Amcheslavsky, S, Takeshita, H, Drissi, Z, Bar-Shavit   +4 more
openaire   +2 more sources

RANK ligand et métastases osseuses

2008
Les cellules tumorales secretent des facteurs osteolytiques dont la plupart agissent via la production par les osteoblastes de RANKL, facteur de la differenciation des osteoclastes.
openaire   +1 more source

[Inhibition of RANK ligand to treat bone metastases].

Bulletin du cancer, 2013
info:eu-repo/semantics ...
openaire   +2 more sources

RANK Ligand

2012
Pedro Tauler Riera, Maurizio Volterrani, Ferdinando Iellamo, Francesco Fallo, Andrea Ermolao, William J. Kraemer, Nicholas A. Ratamess, Avery Faigenbaum, Andrew Philp, Keith Baar   +9 more
openaire   +1 more source

Extraskeletal effects of RANK ligand

2020
Andy Göbel, Tilman D. Rachner, Lorenz C. Hofbauer   +2 more
openaire   +1 more source

Ranking of High‐Affinity Ligands by NMR Spectroscopy

Angewandte Chemie International Edition, 2009
Xiaolu, Zhang, Andrea, Sänger, René, Hemmig, Wolfgang, Jahnke   +3 more
openaire   +2 more sources

Platelet-derived RANK ligand enhances CCL17 secretion from dendritic cells mediated by thymic stromal lymphopoietin

Platelets, 2015
Tomoki Itô, Shosaku Nomura, Akihiro Tanaka   +2 more
exaly  

The High Rate of Bone Resorption in Multiple Myeloma is due to RANK (Receptor Activator of Nuclear Factor-κB) and RANK Ligand Expression

Leukemia and Lymphoma, 2004
Xavier Mariette, Sophie Roux
exaly