Results 241 to 250 of about 1,142,931 (269)

Osteoprotegerin, rank and rank ligand

2007
The discovery of the osteoprotegerin, receptor activator of nuclear factor-kappa B ligand and receptor activator of nuclear factor-kappa B and identification of their role in osteoclastogenesis provided a major advance in bone biology. receptor activator of nuclear factor-kappa B ligand binds to its receptors on the surface of preosteoclasts and ...
Kurban, Sevil, Mehmetoglu, Idris
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Detection and characterization of RANK ligand and osteoprotegerin in the thyroid gland

Journal of Cellular Biochemistry, 2002
AbstractReceptor activator of NF‐κB (RANK) ligand (RANKL) and osteoprotegerin (OPG) play essential roles in bone metabolism and immune responses. RANKL activates RANK, which is expressed by osteoclasts and dendritic cells (DC), whereas OPG acts as its decoy receptor. The role of RANKL and OPG in thyroid physiology is unclear. Northern analysis revealed
Lorenz C, Hofbauer, Sibylle, Kluger, Christian A, Kühne, Colin R, Dunstan, Andreas, Burchert, Michael, Schoppet, Andreas, Zielke, Armin E, Heufelder   +7 more
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RANK ligand is a prerequisite for cancer‐associated osteolytic lesions

The Journal of Pathology, 2002
AbstractBreast cancer is frequently associated with osteolytic bone metastasis, where osteoclasts play a major role in bone destruction. Recently, osteoclast differentiation factor (RANKL) has been identified as a prerequisite for the formation and maintenance of osteoclasts from haematopoietic precursors.
Sohei, Kitazawa, Riko, Kitazawa
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Expression of RANK‐ligand in prostate cancer cell lines

Scandinavian Journal of Clinical and Laboratory Investigation, 2009
The molecular mediators of bone remodelling, receptor activator of nuclear factor-kappaB ligand (RANKL), receptor activator of nuclear factor-kappaB (RANK) and osteoprotegerine (OPG), are believed to be involved in the cellular mechanisms by which tumours metastasize to bone. RANKL is a potent stimulator of osteoclastic bone resorption and is expressed
Hendrik, Penno, Olle, Nilsson, Helena, Brändström, Ola, Winqvist, Osten, Ljunggren   +4 more
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TNF‐α expression is transcriptionally regulated by RANK ligand

Journal of Cellular Physiology, 2004
AbstractTumor necrosis factor (TNF)‐α is known for its osteoclastogenic and resorptive activities. Induction of osteoclastogenesis by receptor activator of NF‐κB ligand (RANKL) is accompanied by increased TNF‐α expression. In the present study we investigated the mechanism by which RANKL induces expression of TNF‐α in osteoclast precursors.
W, Zou, A, Amcheslavsky, S, Takeshita, H, Drissi, Z, Bar-Shavit   +4 more
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RANK ligand et métastases osseuses

2008
Les cellules tumorales secretent des facteurs osteolytiques dont la plupart agissent via la production par les osteoblastes de RANKL, facteur de la differenciation des osteoclastes.
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[Inhibition of RANK ligand to treat bone metastases].

Bulletin du cancer, 2013
info:eu-repo/semantics ...
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RANK Ligand

2012
Pedro Tauler Riera, Maurizio Volterrani, Ferdinando Iellamo, Francesco Fallo, Andrea Ermolao, William J. Kraemer, Nicholas A. Ratamess, Avery Faigenbaum, Andrew Philp, Keith Baar   +9 more
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Extraskeletal effects of RANK ligand

2020
Andy Göbel, Tilman D. Rachner, Lorenz C. Hofbauer   +2 more
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Ranking of High‐Affinity Ligands by NMR Spectroscopy

Angewandte Chemie International Edition, 2009
Xiaolu, Zhang, Andrea, Sänger, René, Hemmig, Wolfgang, Jahnke   +3 more
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