Results 221 to 230 of about 1,142,931 (269)

OPG, RANK and RANK ligand expression in thyroid lesions

open access: yesRegulatory Peptides, 2008
Receptor activator of NF-κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG) play essential roles in bone metabolism. RANKL binds to RANK, which is expressed by osteoclasts whereas OPG acts as its decoy receptor blocking the RANK-RANKL interaction ...
Dominique Heymann   +2 more
exaly   +5 more sources
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RANK Ligand: Effects of Inhibition

Current Oncology Reports, 2010
Receptor activator of nuclear factor kappa-light-chain-enhancer of activated B-cells (RANK) and its ligand (RANKL) belong to the tumor necrosis factor (TNF) superfamily. RANK mRNA is expressed widely in bone and bone marrow. It has a significant role in stimulating osteoclast differentiation and maturation, and also in preventing apoptosis.
Saby George, Ronald M Bukowski
exaly   +3 more sources

RANK ligand

The International Journal of Biochemistry & Cell Biology, 2007
RANK ligand (RANKL), a key mediator of bone resorption in normal and pathological states, is expressed as membrane-bound or soluble forms by tissues as diverse as lymph nodes, spleen, thymus and bone-forming cells. In normal bone turnover and in bone metastasis, RANKL stimulates the formation and activity of bone-removing cells, osteoclasts, by binding
J M, Blair, Y, Zheng, C R, Dunstan
openaire   +2 more sources

Ranking the role of RANK ligand in apoptosis

Apoptosis, 2004
Many members of tumor necrosis factor (TNF) superfamily are characterized by their ability to induce apoptosis once they bind in a homotrimeric manner to their cognate receptors. The receptor activator of nuclear factor-kappaB ligand (RANKL), a member of the TNF superfamily identified seven years ago, was originally described as a factor that induced ...
A C, Bharti, B B, Aggarwal
openaire   +2 more sources

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