Results 281 to 290 of about 88,529 (348)

Skin Lipid–Microbe Interplay Links Staphylococcus hominis to Barrier Control in Adult Atopic Dermatitis

Allergy, Volume 81, Issue 2, Page 454-467, February 2026.
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya, Felix Lauffer, Manja Jargosch, Kristina Frey, Mahsa Shahidi Dadras, Theresa Raunegger, Sophia Wasserer, Carsten B. Schmidt‐Weber, Tilo Biedermann, Kilian Eyerich, Stefanie Eyerich, Claudia Traidl‐Hoffmann, Christian Klose, Matthias Reiger, Natalie Garzorz‐Stark   +14 more
wiley   +1 more source

Xuetongsu attenuates bone destruction in rheumatoid arthritis by suppressing RANKL/RANK/NFATc1 pathway to inhibit osteoclastogenesis and bone resorption. [PDF]

Bone Joint Res
Zheng H, Deng Y, Li B, Huang J, Liu J, Yang Y, Chen Y, Mao L, Li Y, Liu Y, Wang W, Yu H.   +11 more
europepmc   +1 more source

Stromal Defense Against Cancer: An Unprecedented Mechanism Limiting Cancer Invasion Into the Bone

Cancer Science, Volume 117, Issue 2, Page 308-315, February 2026.
The roles of nonimmune systems in tumor regulation remain largely undefined. This article introduces a new concept, “stromal defense against cancer (SDAC),” which is based on recent findings that the periosteum actively responds to tumor proximity and physically impedes tumor invasion into bone.
Masayuki Tsukasaki, Hiroshi Takayanagi
wiley   +1 more source

Hyperbaric oxygen protects against periodontal bone loss by modulating inflammation and bone remodeling via RANKL/OPG expression in ligature-induced periodontitis. [PDF]

Int J Med Sci
Tu KW, Huang CC, Lin MT, Niu KC, Lin CH, Chao PY, Chang CP, Mau JLP.   +7 more
europepmc   +1 more source

HSD17B7 Counters Bone Loss in Estrogen Deficiency via Estrogen Receptor Stabilization and Mediates the Effect of Raloxifene [PDF]

MedComm (2020)
In this study, we identified a previously unrecognized function of HSD17B7 as an ERα‐binding protein that serves as a coactivator to influence trabecular bone mass in estrogen deficiency. Specifically, deleting HSD17B7 in myeloid cells enhanced the number of osteoclasts and decreased trabecular bone mass post‐OVX, compared with control OVX, mirroring ...
Zhang J, Song Y, Koo J, Chen S, Jang K, Yoon S, Kim J, Moon Y.   +7 more
europepmc   +2 more sources

Generation and Purification of RANKL-Derived Small-Fragment Variants for Osteoclast Inhibition. [PDF]

Pharmaceutics
Lee H, Park H, Kim K, Ko Y, Lee CM, Lim W.   +5 more
europepmc   +1 more source

Supplementary Table 3 from Immune Modulation with RANKL Blockade through Denosumab Treatment in Patients with Cancer

Hewitt Chang, Jaqueline Marquez, Brandon K. Chen, Daniel M. Kim, Michael L. Cheng, Eric Liu, Hai Yang, Li Zhang, Meenal Sinha, Alexander Cheung, Serena S. Kwek, Eric D. Chow, Mark Bridge, Rahul Aggarwal, Terence W. Friedlander, Eric J. Small, Mark S. Anderson, Lawrence Fong   +17 more
openalex   +1 more source

Denosumab for Primary Osteoporosis and Its Impact on Sarcopenia in the Chinese Population: Insights from Clinical Evidence and RANKL Pathway Mendelian Randomization. [PDF]

Clin Interv Aging
Li S, Hu S, Zheng X, Ku X, Zou J, Wang L, Nie G, Liu Y, Tian C, Ran J, Yang X, Yan M, Yin Y, Liu Y, Wan J, Peng W.   +15 more
europepmc   +1 more source

LGR4 binding small RANKL fragment inhibits RANKL-induced bone resorption

European Cells and Materials
W Lim, CM Lee, B Kim, H Lee, Y Ko, YJ Cho, Y Jang   +6 more
openaire   +1 more source

Gut Metabolite Indoleacrylic Acid Suppresses Osteoclast Formation by AHR mediated NF-κB Signaling Pathway. [PDF]

Int J Biol Sci
Bai J, Si G, Wang R, Su S, Fan J, He X, Lv Y, Gao S, Zhou F.   +8 more
europepmc   +1 more source