Results 201 to 210 of about 164,975 (264)

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Long-term rapamycin treatment suppresses IL-17-producing gamma delta T cells and blunts neuroinflammation in aging. [PDF]

PLoS One
Torrent C, Gagliardi C, Fülle N, Antignano I, Bernis ME, Stork M, Bano D, Capasso M, Keane L.   +8 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Targeted inhibition of the BDNF/AKT/mTOR pathway in the inferior colliculus ameliorates salicylate-induced tinnitus in rats. [PDF]

iScience
Lin J, Wu J, Wang Y, Huo Y, Zhang J.
europepmc   +1 more source

Targeting mTOR to Mitigate Sequelae of Chronic Hypoxia on the Carotid Artery and Cerebral Circulation. [PDF]

Compr Physiol
Choi R, Mihailovic J, Sharma P, Nikola F, Bluestein SL, Doddaballapur P, Guerrera N, Abu Hussein NS, Cavinato C, Adams TS, Yan X, Hyder F, Herman P, Humphrey JD, Manning EP.   +14 more
europepmc   +1 more source

Crotonylome profiling identifies MLKL crotonylation in lupus nephritis associated with RAB1A-mTOR signalling and autophagy changes in tubular epithelial cells. [PDF]

Lupus Sci Med
Lu RL, Meng SH, Peng QZ, Chen Y, Yang X, Liu HY, Zheng FP, Liu D, Hong X.   +8 more
europepmc   +1 more source

Bench to bedside: is rapamycin headed for the docTOR? [PDF]

Geroscience
Lamming DW.
europepmc   +1 more source

Fpr1p mediates the synergistic effect of rapamycin or tacrolimus with caspofungin in <i>Clavispora lusitaniae in vitro</i>. [PDF]

JAC Antimicrob Resist
Lefranc M, Accoceberry I, Fitton-Ouhabi V, Biteau N, Noël T.   +4 more
europepmc   +1 more source

A Soy-Derived Isoflavone Genistein Inhibits the Life Cycle of PRRSV In Vitro. [PDF]

Int J Mol Sci
Cao D, Huan C, Tang X, Xue Y.
europepmc   +1 more source

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Solubilization of rapamycin

International Journal of Pharmaceutics, 2001
The solubilization of rapamycin, a poorly water soluble investigational immunosuppressive drug, by facilitated hydrotropy is presented. Partially water-miscible aromatic solutes (such as benzyl alcohol, benzoate, or benzoic acid) can be solubilized by water-miscible cosolvents, such as ethanol and propylene glycol.
P, Simamora, J M, Alvarez, S H, Yalkowsky   +2 more
openaire   +2 more sources