Results 201 to 210 of about 257,231 (311)

The nitrogen starvation-induced inhibitor Rts3 restrains Sit4/PP6 to gate quiescence downstream of TORC1. [PDF]

Nat Commun
Dokládal L, Péli-Gulli MP, Alba J, Stumpe M, Jaquenoud M, Klemt I, Jaggi CA, Calviello RL, Hu Z, Siva Sankar D, Peter M, Dengjel J, De Virgilio C.   +12 more
europepmc   +1 more source

Rapamycin's sister [PDF]

Nature Methods, 2012
openaire   +1 more source

Rapamycin protects aging muscle

Aging, 2019
Tang, Huibin, Shrager, Joseph B., Goldman, Daniel   +2 more
openaire   +2 more sources

Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer

International Journal of Cancer, EarlyView.
What's New? Epithelial ovarian cancer (EOC) is a severe malignancy with few effective treatment options. While the mechanisms remain unclear, changes in lipid metabolism may fuel tumor growth and EOC progression, offering a possible path for new treatments.
Hitomi Sakaguchi‐Mukaida, Kosuke Hiramatsu, Tatsuo Masuda, Mamoru Kakuda, Satoshi Nakagawa, Tadashi Iwamiya, Shinya Matsuzaki, Tetsuji Naka, Yutaka Ueda, Tadashi Kimura, Michiko Kodama   +10 more
wiley   +1 more source

Modelling post-traumatic stress disorder-major depressive disorder comorbidity in rats: impaired α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor signalling is consistent with synergistic behavioural and cognitive deficits. [PDF]

Eur J Psychotraumatol
Jiang B, Li S, Yan W, Zheng H, Zhou H, Sun Y, Ma Q, Guo X, Zhao Y, Zhu G, Liu L, Sun L.   +11 more
europepmc   +1 more source

Rapamycin in mice

Aging, 2017
openaire   +2 more sources

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

ZDHHC9 palmitoylates LAMTOR1 to promote renal cell carcinoma malignant progression. [PDF]

Cell Death Dis
Liu B, Hou T, Liu X, Liu L, Ma Z, Zhang Y.   +5 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Regulatory T cells in the era of cell and gene therapy: biology, clinical translation, and future prospects. [PDF]

Front Immunol
Sato Y.
europepmc   +1 more source