Results 231 to 240 of about 257,231 (311)

TRIM7-mediated autophagy-lysosomal signaling is essential for preimplantation development in mice. [PDF]

J Transl Med
Khan S, Yan F, Li W, Guo J, Gu X, Tang Z, Bibi U, Dong X, Chen L, Yao Y, Xu J.   +10 more
europepmc   +1 more source

Triacylglycerol‐Based Insulin Resistance Indices and Post‐Transplantation Diabetes Mellitus After Liver Transplantation

Lipids, EarlyView.
ABSTRACT Background: Post‐transplant diabetes mellitus (PTDM) is a common complication following liver transplant (LT) and is associated with adverse outcomes. The triacylglycerol‐glucose product (TyG) and the triacylglycerol‐to‐high‐density lipoprotein (HDL) cholesterol ratio (TAG/HDL‐c) are indices that can serve as triacylglycerol‐based proxies for ...
Mateo Chvatal‐Medina, Yakun Li, Adrian Post, Margery A. Connelly, Han Moshage, Stephan J. L. Bakker, Vincent E. de Meijer, Hans Blokzijl, Robin P. F. Dullaart, on behalf of TransplantLines investigators   +9 more
wiley   +1 more source

Functional characterisation of Target of Rapamycin (TOR) signalling in Physcomitrella. [PDF]

Plant Cell Rep
Saliba E, Hoernstein SNW, van Gessel N, Sentimenti A, Höß KMV, Parsons J, Decker EL, Huesgen PF, Simonsen HT, Reski R.   +9 more
europepmc   +1 more source

Immunometabolic determinants of long-term response in leukemia patients receiving CD19 CAR T cell therapy. [PDF]

Nat Commun
Goldberg L, Haas ER, Wu J, Garcia B, Urak R, Vyas V, Espinosa R, Munoz T, Bierkatz S, Pathak KV, Hansen NP, Pirrotte P, Singhal J, Figarola JL, Noriega RZ, Li Z, Wi D, Tanaka E, Geltink RK, Chen MH, Wu X, Wagner JR, Paul J, Clark MC, Ngo D, Aldoss I, Forman SJ, Wang X.   +27 more
europepmc   +1 more source

Protocol for microinjection of rapamycin into the zebrafish habenula. [PDF]

STAR Protoc
Doszyn O, Dulski T, Zmorzynska J.
europepmc   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

Yeast Chronological Lifespan Model as a Tool for Screening Aging Interventions. [PDF]

Int J Mol Sci
Xu P, Zhang X, Wang Y, Rahman SU, Huang D, Wu Z.   +5 more
europepmc   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Membrane-camouflaged nanoparticle alleviates intervertebral disc degeneration via oxidative stress suppression and autophagy activation. [PDF]

Mater Today Bio
Niu Z, Fan Y, Chen J, Ji L, Tong Y, Yao L, Ding S, Xu H, Chen J, Zhang Q, Zhao C, Chen J, Bi Q, Xia C.   +13 more
europepmc   +1 more source

Seeing Invisible Oligomers: Rethinking α‐Synuclein Pathology Through Proximity Ligation Assay

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) and multiple system atrophy are defined by α‐synuclein (αSYN)‐positive inclusions – Lewy bodies (LBs) and glial cytoplasmic inclusions – yet mounting evidence indicates that these inclusions represent only a fraction of disease‐relevant pathology.
Hiroaki Sekiya, Nanna Møller Jensen, Dennis W. Dickson, Poul Henning Jensen   +3 more
wiley   +1 more source