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Rapid Antimicrobial Susceptibility Testing Methods for Blood Cultures and Their Clinical Impact [PDF]

open access: yesFrontiers in Medicine, 2021
Antimicrobial susceptibility testing (AST) of bacteria isolated in blood cultures is critical for optimal management of patients with sepsis. This review describes new and emerging phenotypic and genotypic AST methods and summarizes the evidence that ...
Ritu Banerjee, Romney Humphries
doaj   +7 more sources

Beating the Bio-Terror Threat with Rapid Antimicrobial Susceptibility Testing [PDF]

open access: yesMicroorganisms, 2021
A bioterror event using an infectious bacterium may lead to catastrophic outcomes involving morbidity and mortality as well as social and psychological stress.
Shahar Rotem   +4 more
doaj   +5 more sources

Clinical and Financial Impact of Rapid Antimicrobial Susceptibility Testing in Blood Cultures [PDF]

open access: yesAntibiotics, 2022
The rapid identification of pathogens that cause bloodstream infections plays a vital role in the modern clinical microbiology laboratory. Despite demonstrating a significant reduction in turnaround time and a significant effect on clinical decisions ...
Felix Roth   +3 more
doaj   +5 more sources

Portable Dynamic Laser Speckle Imaging for Rapid Antimicrobial Susceptibility Testing [PDF]

open access: yesECS Sensors Plus
Antimicrobial resistance remains a pressing global health threat. Conventional antimicrobial susceptibility testing (AST) methods are limited by long incubation times and centralized laboratory requirements, hindering timely decision-making in resource ...
Jinkai Yang   +7 more
doaj   +3 more sources

Phenotypic Ultra-Rapid Antimicrobial Susceptibility Testing for Ceftazidime–Avibactam: In Support of Antimicrobial Stewardship [PDF]

open access: yesMicroorganisms
Ceftazidime–avibactam (CZA) is a potent broad-spectrum drug combination covering extended-spectrum β-lactamases, AmpC, and carbapenemases of class A and D, OXA-48-type producers.
Inês Martins-Oliveira   +6 more
doaj   +4 more sources

Rapid Bead-Based Antimicrobial Susceptibility Testing by Optical Diffusometry. [PDF]

open access: yesPLoS ONE, 2016
This study combined optical diffusometry and bead-based immunoassays to develop a novel technique for quantifying the growth of specific microorganisms and achieving rapid AST.
Chih-Yao Chung   +2 more
doaj   +6 more sources

Rapid ultrasensitive detection platform for antimicrobial susceptibility testing.

open access: yesPLoS Biology, 2019
Rapid detection and phenotyping of pathogenic microbes is critical for administration of effective antibiotic therapies and for impeding the spread of antibiotic resistance.
Mehmet F Cansizoglu   +4 more
doaj   +4 more sources

Next-generation rapid phenotypic antimicrobial susceptibility testing

open access: yesNature Communications
Slow progress towards implementation of conventional clinical bacteriology in low resource settings and strong interest in greater speed for antimicrobial susceptibility testing (AST) more generally has focused attention on next-generation rapid AST ...
Grace Reszetnik   +9 more
doaj   +3 more sources

A Rapid Single-Cell Antimicrobial Susceptibility Testing Workflow for Bloodstream Infections [PDF]

open access: yesBiosensors, 2021
Bloodstream infections are a significant cause of morbidity and mortality worldwide. The rapid initiation of effective antibiotic treatment is critical for patients with bloodstream infections.
Britney Forsyth   +9 more
doaj   +3 more sources

Evaluation of phage assay for rapid phenotypic detection of rifampicin resistance in Mycobacterium tuberculosis [PDF]

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2006
Background Conventional methods for susceptibility testing require several months before results can be reported. However, rapid methods to determine drug susceptibility have been developed recently. Phage assay have been reported as a rapid useful tools
Montoro Ernesto   +6 more
doaj   +4 more sources

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