Beating the Bio-Terror Threat with Rapid Antimicrobial Susceptibility Testing [PDF]
Microorganisms, 2021 A bioterror event using an infectious bacterium may lead to catastrophic outcomes involving morbidity and mortality as well as social and psychological stress.
Shahar Rotem +4 more
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Clinical and Financial Impact of Rapid Antimicrobial Susceptibility Testing in Blood Cultures [PDF]
Antibiotics, 2022 The rapid identification of pathogens that cause bloodstream infections plays a vital role in the modern clinical microbiology laboratory. Despite demonstrating a significant reduction in turnaround time and a significant effect on clinical decisions ...
Felix Roth +3 more
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Evaluation of FASTinov for rapid antimicrobial susceptibility testing in Pseudomonas aeruginosa [PDF]
Scientific ReportsPseudomonas aeruginosa is a critical priority pathogen due to its high resistance rates and limited treatment options. Rapid antimicrobial susceptibility testing (rAST) is essential to optimize therapy, particularly because resistance mechanisms in P ...
Carmen Cintora-Mairal +4 more
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Portable Dynamic Laser Speckle Imaging for Rapid Antimicrobial Susceptibility Testing [PDF]
ECS Sensors PlusAntimicrobial resistance remains a pressing global health threat. Conventional antimicrobial susceptibility testing (AST) methods are limited by long incubation times and centralized laboratory requirements, hindering timely decision-making in resource ...
Jinkai Yang +7 more
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Phenotypic Ultra-Rapid Antimicrobial Susceptibility Testing for Ceftazidime–Avibactam: In Support of Antimicrobial Stewardship [PDF]
MicroorganismsCeftazidime–avibactam (CZA) is a potent broad-spectrum drug combination covering extended-spectrum β-lactamases, AmpC, and carbapenemases of class A and D, OXA-48-type producers.
Inês Martins-Oliveira +6 more
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Rapid Antimicrobial Susceptibility Testing Methods for Blood Cultures and Their Clinical Impact [PDF]
Frontiers in Medicine, 2021 Antimicrobial susceptibility testing (AST) of bacteria isolated in blood cultures is critical for optimal management of patients with sepsis. This review describes new and emerging phenotypic and genotypic AST methods and summarizes the evidence that ...
Ritu Banerjee, Romney Humphries
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Innovative and rapid antimicrobial susceptibility testing systems [PDF]
Nature Reviews Microbiology, 2020 Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid detection and quantification of resistance, combined with antimicrobial stewardship, are key interventions to combat the spread and emergence of AMR. Antimicrobial susceptibility testing (AST) systems are the collective set of diagnostic processes that facilitate ...
Alex Van Belkum +2 more
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Rapid Bead-Based Antimicrobial Susceptibility Testing by Optical Diffusometry. [PDF]
PLoS ONE, 2016 This study combined optical diffusometry and bead-based immunoassays to develop a novel technique for quantifying the growth of specific microorganisms and achieving rapid AST.
Chih-Yao Chung +2 more
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Rapid ultrasensitive detection platform for antimicrobial susceptibility testing.
PLoS Biology, 2019 Rapid detection and phenotyping of pathogenic microbes is critical for administration of effective antibiotic therapies and for impeding the spread of antibiotic resistance.
Mehmet F Cansizoglu +4 more
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Next-generation rapid phenotypic antimicrobial susceptibility testing
Nature CommunicationsSlow progress towards implementation of conventional clinical bacteriology in low resource settings and strong interest in greater speed for antimicrobial susceptibility testing (AST) more generally has focused attention on next-generation rapid AST ...
Grace Reszetnik +9 more
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