Results 91 to 100 of about 4,993,770 (270)

Sorting of Live/dead Escherichia Coli by Means of Dielectrophoresis for Rapid Antimicrobial Susceptibility Testing

, 2023
According to the World Health Organization (WHO) forecasts, AntiMicrobial Resistance (AMR) will represent the leading cause of death worldwide in the next decades.
Ciminelli, C., Armenise, M. N., Sasanelli, N., Brunetti, G., di Toma, A.   +4 more
core   +1 more source

Evaluation of phage assay for rapid phenotypic detection of rifampicin resistance in Mycobacterium tuberculosis

Annals of Clinical Microbiology and Antimicrobials, 2006
Background Conventional methods for susceptibility testing require several months before results can be reported. However, rapid methods to determine drug susceptibility have been developed recently. Phage assay have been reported as a rapid useful tools
Montoro Ernesto, Echemendia Miguel, Lemus Dihadenys, Yzquierdo Sergio, McNerney Ruth, Martin Anandi, Palomino Juan   +6 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Bloodstream Infection due to Piperacillin/Tazobactam Non-Susceptible, Cephalosporin-Susceptible Escherichia coli: A Missed Opportunity for De-Escalation of Therapy

Antibiotics, 2018
An increasing number of reports describing Escherichia coli isolates with piperacillin/tazobactam resistance, despite retained cephalosporin susceptibility, suggest further emergence of this phenotypic resistance pattern.
Leah Carlisle, Julie Ann Justo, Majdi N. Al-Hasan   +2 more
doaj   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Raman-Based Antimicrobial Susceptibility Testing on Antibiotics of Last Resort

, 2023
Zhirou Xiao,1,* Liping Qu,2,* Haijun Chen,1 Wanting Liu,2 Yi Zhan,2 Jiahui Ling,2 Hongwei Shen,3 Ling Yang,1 Dingqiang Chen2 1Department of Laboratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong ...
Yang L, Xiao Z, Qu L, Chen H, Ling J, Shen H, Liu W, Zhan Y, Chen D   +8 more
core  

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Performance of direct rapid antimicrobial susceptibility testing on urine [PDF]

, 2020
Urinary tract infections (UTIs) are a medical threat with the high morbidity of 150 million people worldwide a year. UTIs like other infections are treated with the broad-spectrum antibiotics which consequently leads to the increase of resistances and ...
Mugiraneza, Justin
core  

Research Progress on Novel Antimicrobial Susceptibility Testing Methods

Xiehe Yixue Zazhi
Antimicrobial susceptibility testing (AST) helps guide clinical rational selection of antibiotics, enabling patients to achieve better prognosis and reducing the development of drug resistance.
ZHAO Ying, XU Yingchun
doaj   +1 more source