Results 71 to 80 of about 114,003 (287)

Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: A pivotal interplay in the pathogenesis of Atopic Dermatitis [PDF]

, 2018
Individuals with Atopic dermatitis (AD) are highly susceptible to Staphylococcus aureus colonization. However, the mechanisms driving this process as well as the impact of S. aureus in AD pathogenesis are still incompletely understood.
A Matlow, A Oliveira de, A Sandilands, A Sonesson, AC Krakowski, AD Irvine, AM Bowcock, B Cabanillas, B Han, BC Friedman, C Fux, C Pascolini, CI Ewing, CL Jinnestal, D Ellinghaus, D Lebeaux, DY Koller, DYM Leung, DYM Leung, E Clark, E Weinberg, EC Clark, EG Domenico Di, EG Domenico Di, FJ Bath-Hextall, FR Menegotto, G Stinco, GF Gad, GL Hazelbauer, GM O’Regan, GM O’Regan, GU Meduri, H Akiyama, HB Allen, HH Kong, I Marenholz, I Nomura, J Oh, J Schmitt, JH Lee, JM Hanifin, JQ Gong, K Becker, K Breuer, K Krause, KL Hon, L Chronopoulou, L Paternoster, LA O’Neill, LP Girard, M Bhattacharya, M Denis, M Mehrotra, M Niebuhr, MD Howell, ML Schuttelaar, MS Haque, P Castaneda, P Chavant, PH Hoeger, R Lever, R Saginur, RA McLaughlin, RL Gallo, RM Klevens, RP Howlin, S Eriksson, S Kanangat, S Kezic, S Kezic, S Stutte, S Weidinger, SE Hill, SE Satorres, SE Satorres, SH Cho, SH Hung, SJ Gilani, SX Xu, T Bieber, T Biedermann, T Kobayashi, T Nakatsuji, T Werfel, TX Nhan, UG Meduri, V Dossow von, W Abramovits, Z Ikezawa   +88 more
core   +1 more source

Deep learning for rapid, single-cell antimicrobial susceptibility testing

, 2023
The rise of antimicrobial resistance (AMR) is one of the most pressing global healthcare challenges, already causing an estimated 1.2 million preventable deaths annually and rising. Crucial to the management of AMR is rapid and specific diagnosis, allowing early and optimized intervention.
openaire   +2 more sources

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Rapid antibiotic susceptibility testing from blood culture bottles with species agnostic real-time polymerase chain reaction.

PLoS ONE, 2018
Development and implementation of rapid antimicrobial susceptibility testing is critical for guiding patient care and improving clinical outcomes, especially in cases of sepsis.
Tucker Maxson, Candace D Blancett, Amanda S Graham, Christopher P Stefan, Timothy D Minogue   +4 more
doaj   +1 more source

Clinical impact of the accelerate PhenoTest® BC system on patients with gram-negative bacteremia and high risk of antimicrobial resistance: a prospective before-after implementation study

Annals of Clinical Microbiology and Antimicrobials, 2023
Background The Accelerate PhenoTest® BC system (AXDX) is a novel assay for rapid bacterial identification and antimicrobial susceptibility (AST). We report an evaluation of its impact on treatment of patients with Gram-negative bacteremia (GNB) with a ...
Tal Brosh-Nissimov, Anka Tzur, Daniel Grupel, Amos Cahan, Nir Ma’aravi, Maya Heled-Akiva, Hasan Jawamis, Hanna Leskes, Erez Barenboim, Nadav Sorek   +9 more
doaj   +1 more source

Accuracy of Broad-Panel PCR-Based Bacterial Identification for Blood Cultures in a Pediatric Oncology Population

Microbiology Spectrum, 2021
Bloodstream infections are a major cause of morbidity and mortality and result in significant costs to health care systems. Rapid identification of the causative agent of bloodstream infections is critical for patient treatment and improved outcomes ...
C. D. Garner, J. Brazelton de Cardenas, S. Suganda, R. T. Hayden   +3 more
doaj   +1 more source

Does microbicide use in consumer products promote antimicrobial resistance? A critical review and recommendations for a cohesive approach to risk assessment [PDF]

, 2013
The increasing use of microbicides in consumer products is raising concerns related to enhanced microbicide resistance in bacteria and potential cross resistance to antibiotics.
Bloomfield, Sally, Coelho, Joana Rosado, Collier, Phillip J., Cookson, Barry, Fanning, Séamus, Hartemann, Philippe, Hill, Andrew, Maillard, Jean-Yves, Mcbain, Andrew J., Oggioni, Marco, Sattar, Syed, Schweizer, Herbert P., Threlfall, John   +12 more
core   +3 more sources

Thermo‐Fluorescent Bactericidal Quantum Dots Based Smart Multifunctional Textiles via Molecular Surface Engineering and 3D‐Printed Interlocked Architectures

Advanced Healthcare Materials, EarlyView.
A versatile approach is presented for fabricating smart multifunctional textiles by integrating thermo‐fluorescent carbon dot/polymer nanocomposite coatings with 3D‐printed interlocked architectures. The fabrics exhibit temperature‐responsive fluorescence, durable hydrophobicity, strong antibacterial and antioxidant activity, and enhanced UV protection.
Poushali Das, Sayan Ganguly, Parham Khoshbakht Marvi, Misha Muthalali, Fatemeh Parniani, Shiza Hassan, Xiaowu (Shirley) Tang, Seshasai Srinivasan, Amin Reza Rajabzadeh   +8 more
wiley   +1 more source

Growth independent morphometric machine learning workflow for single-cell antimicrobial susceptibility testing of Klebsiella pneumoniae to meropenem

Frontiers in Imaging
IntroductionMultidrug-resistant Enterobacteriaceae are among the most urgent global public health threats associated with various life-threatening infections.
Kristel C. Tjandra, Nikhil Ram-Mohan, Manuel Roshardt, Elizabeth J. Zudock, Zhaonan Qu, Kathleen E. Mach, Okyaz Eminaga, Joseph C. Liao, Joseph C. Liao, Samuel Yang, Pak Kin Wong, Pak Kin Wong   +11 more
doaj   +1 more source

Rapid Detection of Plasmid AmpC Beta-Lactamases by a Flow Cytometry Assay

Antibiotics, 2022
Plasmidic AmpC (pAmpC) enzymes are responsible for the hydrolysis of extended-spectrum cephalosporins but they are not routinely investigated in many clinical laboratories.
Inês Martins-Oliveira, Blanca Pérez-Viso, Ana Silva-Dias, Rosário Gomes, Luísa Peixe, Ângela Novais, Rafael Cantón, Cidália Pina-Vaz   +7 more
doaj   +1 more source