Results 91 to 100 of about 2,571,409 (303)

Berberine, a Natural Compound That Demonstrates Antiviral Effects Against Ostreid Herpesvirus 1 Infection in Anadara broughtonii

Viruses
Ostreid herpesvirus 1 (OsHV-1) infection is the primary viral disease responsible for large-scale mortality in bivalve mollusks worldwide, and effective strategies to control the outbreaks of this disease are still lacking.
Hui-Gang Kang, Mao-Le Wei, Jing-Li Wang, Cui-Ping Ma, Xiang Zhang, Bo-Wen Huang, Lu-Sheng Xin, Chang-Ming Bai   +7 more
doaj   +1 more source

Effect of Replacing Milk Fat with Soybean Oil Bodies on Milk Stability and Yogurt Quality [PDF]

Shipin Kexue
In this study, the stability of cow’s milk with fat replacement by soybean oil bodies (SOB) was investigated under different environmental conditions.
HE Shenghua, ZHOU Sanjiu, WANG Yonghui, LI Guanghui, GAO Xueli, HUANG Jihong, GUO Weiyun
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Rapid Detection of Avian Eimeria Species Using Denaturing Gradient Gel Electrophoresis [PDF]

, 2008
A denaturing gradient gel electrophoresis (DGGE) assay was developed to rapidly discriminate species of avian Eimeria. Amplification by PCR of the small subunit ribosomal RNA gene (approximately 1,600 nucleotides) with Eimeria genus-specific primers ...
Hume, M. E., Martynova-Van Kley, Alexandra, Nalian, A., Syvyk, A., Teplova, I.   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Cloning of the Coat Protein Gene of Little Cherry Virus 1 and the Preparation of a Polyclonal Antibody

International Journal of Fruit Science
Little cherry disease (LChD) is a serious viral disease that significantly reduces the yield and quality of sweet cherries. And Little cherry virus 1 (LChV-1) is a major pathogen. To facilitate the rapid and efficient detection of LChV-1, we successfully
Wei Li, Qinwang Shang, Xiaohou Xu, Qingle Chang, Deya Wang   +4 more
doaj   +1 more source

PyCBC Live: Rapid Detection of Gravitational Waves from Compact Binary Mergers

, 2018
We introduce an efficient and straightforward technique for rapidly detecting gravitational waves from compact binary mergers. We show that this method achieves the low latencies required to alert electromagnetic partners of candidate binary mergers ...
Canton, Tito Dal, Davis, Derek, Nitz, Alexander H., Reyes, Steven   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Rapid identification of Lonicera japonica via Proofman-LMTIA technology

Scientific Reports
The study introduces a novel, rapid and precise method for identifying Lonicera japonica (JYH), an important medicinal herb, utilizing Proofman-LMTIA (Proofman probe-ladder melting temperature isothermal amplification) technology. Based on the 5.8 S-ITS2
Xiaodong Zhang, Caixia Li, Dejia Lan, Jinxin Liu, Deguo Wang   +4 more
doaj   +1 more source