Results 161 to 170 of about 5,593,091 (310)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Pactola Dam Construction Crew, Silver City, Pennington County
, 1956 4 x 5 photograph, workmen posing with their construction vehiclesMiscellaneous Subject File Black Hills Accommodations, Caves, Harney Peak, Lakes P77 Tab Lakes Black Hills Poster board Pactola Dam P77 [stamp] Property of South Dakota State Historical ...
Rapid City Journal
core
Development of colloidal gold and carbon immunochromatographic strips for rapid detection of PDCoV. [PDF]
iScienceHao C +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Rapid detection of Chlamydia Psittaci by isothermal recombinase polymerase amplification assays. [PDF]
Poult SciZhang X +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Pactola Dam Construction Site, Silver City, Pennington County
, 1956 4 x 5 photograph, view of bodies of water and an open area beyond the waterMiscellaneous Subject File Black Hills Accommodations, Caves, Harney Peak, Lakes P77 Tab Lakes Black Hills Poster board Pactola Dam P77 [stamp] Property of South Dakota State ...
Rapid City Journal
core
Research on a rapid detection method for systemic lupus erythematosus based on Raman spectroscopy. [PDF]
Front ImmunolRao J, Lin Y, Zhong X, Huang Z, Xiong D.
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source