Results 171 to 180 of about 5,593,091 (310)

Blizzard of 1949, Rapid City, Pennington County

open access: yes, 1949
3 x 5 photograph, two vehicles parked in the middle of drifting snow near a Sinclair service stationTowns Rapid City - Redfield P36 Poster board Rapid City P36 [stamp] Property of South Dakota State Historical Society Pierre, South Dakota [stamp] Give ...

core  

Peroxidase-Mimicking Nanozymes for Rapid Detection of Infectious Diseases. [PDF]

open access: yesAdv Sci (Weinh)
Shao S   +5 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Slope at Pactola Dam Construction Site, Silver City, Pennington County

open access: yes, 1956
4 x 5 photograph, construction vehicles parked at the base of a tall hill, part of the hill has been shaped in preparation for the damMiscellaneous Subject File Black Hills Accommodations, Caves, Harney Peak, Lakes P77 Tab Lakes Black Hills Poster board
Rapid City Journal
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

PdCu@rGO-based Electrochemical Sensor for Rapid Detection of Catechol. [PDF]

open access: yesSensors (Basel)
Shen X   +6 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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