Results 101 to 110 of about 1,683,430 (357)

Intergration of control chart and pattern recognizer for bivariate quality control [PDF]

open access: yes, 2015
Monitoring and diagnosis of mean shifts in manufacturing processes become more challenging when involving two or more correlated variables. Unfortunately, most of the existing multivariate statistical process control schemes are only effective in rapid ...
Mohd Sohaimi, Nurul Adlihisam
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Research progress in detection techniques of common pathogenic bacteria in aquatic products

open access: yesShipin yu jixie
Aquatic products are an essential source of nutrition for humans, and their safety has attracted much attention due to the contaminations with pathogenic bacteria.
XU Meijin, LIN Haisheng, HUANG He
doaj   +1 more source

Emotional and cognitive changes during and post a near fatal heart attack and one-year after: A case study [PDF]

open access: yes, 2010
This case study reports on changes in emotions before and during an unexpected heart rate in a young, apparently healthy male with a life-long history of exercise in the absence of family history of heart problems.
Godfrey, R, Lane, AM
core   +2 more sources

Rapid diagnosis of lung infections

open access: yesNature Biotechnology, 2019
Nanopore sequencing of the sputum metagenome identifies respiratory pathogens in six hours.
Andrei Prodan   +2 more
openaire   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Effective Dexmedetomidine Dose for Stage N2 Sleep Induction and Associated Factors in Depression-Related Insomnia: A Polysomnography-Based Analysis

open access: yesNature and Science of Sleep
Yaozu Li,1– 4 Muyan Zuo,1– 4 Ruoguo Wang,2,3 Yongxiang Li,2,3 John P Williams,5 Jianxiong An1– 5 1Medical School, University of Chinese Academy of Sciences, Beijing, People’s Republic of China; 2Center for Pain & Sleep Medicine, Affiliated Hospital ...
Li Y   +5 more
doaj  

Cost utility analysis of diagnostic method of syphilis [PDF]

open access: yes, 2008
Presently, the diagnosis of syphilis is dependent mainly on serological tests. The most widely used screening tests for syphilis are the VDRL and the rapid plasma reagin (RPR) and for confirmation, the fluorescent treponemal antibody (FTA) and the ...
Wiwanitkit, Viroj
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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