Results 81 to 90 of about 1,840,121 (280)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Rapid Manufacturing of Patient-specific Shielding Masks, using RP in parallel with Metal Spraying

, 2005
Published ArticleThe purpose of the present work is to develop a methodology to manufacture patient‐specific models (lead masks) to be used as protective shields during cancer treatment, using 3D photography, rapid prototyping (RP) and metal spraying. It
Booysen, Gerrie J., Truscott, Michéle, de Beer, Deon J., Barnard, Ludrick J., van der Walt, Jakobus G.   +4 more
core  

Microstructure evolution and hard phase formation in boron-containing tool steels for additive manufacturing

Materials & Design
This study investigates the processability and microstructure formation of carbon-martensitic FeCB-based tool steels, designed for powder bed fusion-laser/metal (PBF-LB/M) with 6, 8, and 10 mass% chromium.
H. Sohaib, H.M. Schaefer, J. Lentz, S. Weber, A. Röttger   +4 more
doaj   +1 more source

Rapid solidification of steel droplets with different carbon contents in drop tube [PDF]

China Foundry, 2012
Rapid solidification is regarded as being an effective method to refine the microstructure and reduce or eliminate the segregation of alloying elements.
Li Na, Sha Minghong, Xu Qian
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Design of Novel HS/HC/HT Twitch Aluminum Alloys

Engineering Proceedings
The design of novel high-strength (HS), high-electrical-conductivity (HC) and high-thermostability (HT) aluminum alloys is presented utilizing recycled automotive aluminum twitch for cable conductor applications.
Maria-Ioanna T. Tzini, Gregory B. Olson
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Solidification behavior of intensively sheared hypoeutectic Al-Si alloy liquid [PDF]

, 2010
The official published version of this article can be found at the link below.The effect of the processing temperature on the microstructural and mechanical properties of Al-Si (hypoeutectic) alloy solidified from intensively sheared liquid metal has ...
H. R. Kotadia, H. Zhang, S. Arumuganathar, Arumuganathar, S, Z. Fan, Kotadia, HR, Hari Babu, N, Zhang, H, Fan, Z, N. Hari Babu   +9 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Electromagnetic levitation containerless processing of metallic materials in microgravity: rapid solidification. [PDF]

NPJ Microgravity, 2023
Matson DM, Battezzati L, Galenko PK, Gandin CA, Gangopadhyay AK, Henein H, Kelton KF, Kolbe M, Valloton J, Vogel SC, Volkmann T.   +10 more
europepmc   +1 more source