Results 31 to 40 of about 511 (127)

Predictors of outcome in idiopathic rapidly progressive glomerulonephritis (IRPGN)

open access: yesBMC Nephrology, 2006
Background Small vessel vasculitides are known to follow a devastating course towards end-stage renal disease, unless treated with immunosuppressive regiments.
Leontsini Maria   +5 more
doaj   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

open access: yesActa Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn   +3 more
wiley   +1 more source

Etiology and outcome of rapidly progressive glomerulonephritis in children

open access: yesJournal of Pediatric Critical Care, 2019
Introduction: Rapidly progressive glomerulonephritis( RPGN) in children is an uncommon entity. There is paucity of studies on this. It is diagnosed with clinical features of oliguria, hematuria and renal failure in weeks.
Alok Kumar   +3 more
doaj   +1 more source

Soluble Immune Checkpoints and Anti‐HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function

open access: yesImmunology, EarlyView.
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu   +8 more
wiley   +1 more source

Targeting the miR‐224‐5p/PTEN pathway: A previously under‐characterized strategy to attenuate mesangial cell injury and predict prognosis in diabetic nephropathy

open access: yesJournal of Diabetes Investigation, EarlyView.
Serum miR‐224‐5p levels are progressively elevated in diabetic nephropathy (DN) and serve as an independent predictor of a decline in eGFR of ≥30% over 2 years. Mechanistically, miR‐224‐5p directly targets PTEN 3’‐UTR, suppressing PTEN and the activation of the AKT pathway in high‐glucose‐stimulated mesangial cells.
Yanxia Gao   +3 more
wiley   +1 more source

Secondary syphilis associated crescentic glomerulonephritis: A case report

open access: yesHuman Pathology Reports, 2021
Introduction: Syphilis is a sexually transmitted disease caused by the bacterium Treponema Pallidum and has a diverse clinical presentation, including nephropathies, the most common of which is membranous nephropathy. Crescentic glomerulonephritis is not
Marcelo Santos Sampaio   +5 more
doaj   +1 more source

AL Amyloidosis Presenting With Crescentic Glomerulonephritis

open access: yesKidney Medicine, 2021
Kidney amyloidosis typically presents with nephrotic-range proteinuria. Rare cases of crescentic glomerulonephritis have been reported in patients with kidney amyloidosis but most cases were in the setting of patients with AA amyloidosis from long ...
Ann A. Wang   +3 more
doaj   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao   +4 more
wiley   +1 more source

The Src‐Family Kinases Hck, Fgr and Lyn Drive Immune Complex‐Mediated Glomerulonephritis Through the Syk Tyrosine Kinase

open access: yesThe FASEB Journal, Volume 40, Issue 16, 31 August 2026.
The study aimed to test the role of three Src‐family kinases, Hck, Fgr, and Lyn in immune complex glomerulonephritis. Hck, Fgr, and Lyn were overexpressed in human lupus nephritis and mouse nephrotoxic nephritis. Combined genetic deficiency of the three kinases practically completely protected mice from nephrotoxic nephritis.
Lukács S. Lesinszki   +6 more
wiley   +1 more source

HIZLI SEYİRLİ, KRESENTİK IgA NEFROPATİLİ BİR OLGU

open access: yesTurkish Journal of Nephrology, 2019
The case which was followed up in our clinic as acute renal failure, malignant hlpertension, microscopic hematuria and rapid deterioration of renal functions had a diagnosis of crescentic form IgA nephropathy by the renal needle biopsy is presented in ...
Mahmut YAVUZ   +5 more
doaj  

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