Results 51 to 60 of about 511 (127)

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source

MPO-ANCA associated crescentic glomerulonephritis with numerous immune complexes: case report

BMC Nephrology, 2012
Background Antineutrophil cytoplasmic antibody (ANCA)-associated crescentic glomerulonephritis (CGN) is a major cause of rapidly progressive glomerulonephritis (RPGN). ANCA-associated CGN is generally classified into pauci-immune RPGN, in which there are
Morizane Ryuji, Konishi Konosuke, Hashiguchi Akinori, Tokuyama Hirobumi, Wakino Shu, Kawabe Hiroshi, Hayashi Matsuhiko, Hayashi Koichi, Itoh Hiroshi   +8 more
doaj   +1 more source

A Combined Transcriptomics and Proteomics Approach to Identify Immune Signatures in ANCA‐Associated Glomerulonephritis

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis often leads to severe kidney damage. To better understand ANCA‐associated glomerulonephritis (AAGN) and identify potential new therapeutic targets, we performed comprehensive transcriptomic and compartmental proteomic analysis of kidney biopsies from 23 patients in the ...
Ivana Stojkic, John P. Shapiro, Arnon Arazi, Huijuan Song, Pearlly Yan, Estela Puchulu‐Campanella, Hubao Wang, William E. Smoyer, Lynn A. Fussner, Anjali Satoskar, Xin Wang, Samir V. Parikh, Stacy P. Ardoin, Dan Koboldt, Brad H. Rovin, Salem Almaani   +15 more
wiley   +1 more source

Pityriasis Lichenoides: Comparison of Two Pediatric Patients and Its Relationships With Vaccines and Infections

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Pityriasis lichenoides (PL) is a benign, self‐limiting inflammatory condition, characterized by the appearance of papular, scaly, or necrotic lesions. Despite the rare incidence, clinicians should suspect its diagnosis in the presence of specific skin lesions and epidemiological contexts, as suggested by its association with infections and/or ...
Gregorio Serra, Deborah Bacile, Elisabetta Di Leto, Ornella Iacono Fullone, Chiara Martorana, Ilaria Pirrone, Mario Tumminello, Giovanni Corsello   +7 more
wiley   +1 more source

IgA vasculitis in an adult diabetic male with rapidly progressive glomerulonephritis: A case study

Journal of Acute Disease
Rationale: IgA vasculitis or Henoch-Schonlein purpura is an immune complex mediated small vessel vasculitis characterized by clinical triad of arthritis, palpable purpura and gastrointestinal symptoms.
Varsha Luthra, Aprajita Garg, Anjali Yadav, Tarun Chaudhary, Monica Gupta   +4 more
doaj   +1 more source

Immune complex-mediated rapidly progressive glomerulonephritis in a patient with family history of systemic lupus erythematosus

Saudi Journal of Kidney Diseases and Transplantation, 2018
We describe here a case of a 53-year-old Saudi female who presented to the emergency room with shortness of breath progressive in nature for the previous one month, associated with a cough and occasional greenish sputum.
Ahmad Alflaiw, Ghormallah Alghamdi, Khalid Alsaad, Noura Aloudah   +3 more
doaj   +1 more source

Acute Lymphoblastic Leukemia Presenting With Severe Acute Kidney Injury Requiring Hemodialysis due to Kidney Infiltration: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT A 66‐year‐old man presented with dialysis‐dependent acute kidney injury without cytopenia or peripheral blasts. Kidney biopsy revealed leukemic infiltration and led to the diagnosis of Philadelphia chromosome‐negative B‐acute lymphoblastic leukemia.
Semin Cho, Soyean Kwon, Jeong Hwan Park, Jin Hyun Park, Ki Hwan Kim, Jin Soo Kim, Eun Youn Roh, In Sil Choi, Ji Eun Kim, Song Yi Park   +9 more
wiley   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, Volume 2, Issue 3, July 2026.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Frosted branch angiitis associated with rapidly progressive glomerulonephritis.

Indian Journal of Ophthalmology, 2002
Simultaneous occurrence of frosted branch angiitis and immune-mediated rapidly progressive glomerulonephritis is reported. The two diseases possibly share a common immune mechanism.
Gupta Amod, Narang Subina, Gupta Vishali, Minz Ranjana, Sakhuja Vinay   +4 more
doaj  

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni, Ebba Qviberg, Edward Chaloner, Hayley Lavender, Maisem Laabei   +4 more
wiley   +1 more source