Results 31 to 40 of about 486,973 (258)

CARCINOMA COLON SIGNET-RING CELL TYPE: A RARE CASE REPORT

Era's Journal of Medical Research, 2022
Carcinoma colon ranks third among the commonest cancer in the world, while seen less common in the Asian countries however lately an increasing trend has been observed. Majorly the elderly population is at an increased risk of colon cancer however early onset of the disease has also been observed in past few years.
Shivangi Shukla, Jyoti Jaiswal, Saba Naziya, Garima Shukla, Priyanka Verma, Nirupma Lal   +5 more
openaire   +1 more source

VBASS enables integration of single cell gene expression data in Bayesian association analysis of rare variants

Communications Biology, 2023
Rare or de novo variants have substantial contribution to human diseases, but the statistical power to identify risk genes by rare variants is generally low due to rarity of genotype data.
Guojie Zhong, Yoolim A. Choi, Yufeng Shen   +2 more
doaj   +1 more source

How many markers are needed to robustly determine a cell's type?

iScience, 2021
Summary: Our understanding of cell types has advanced considerably with the publication of single-cell atlases. Marker genes play an essential role for experimental validation and computational analyses such as physiological characterization, annotation,
Stephan Fischer, Jesse Gillis
doaj   +1 more source

PanoView: An iterative clustering method for single-cell RNA sequencing data.

PLoS Computational Biology, 2019
Single-cell RNA-sequencing (scRNA-seq) provides new opportunities to gain a mechanistic understanding of many biological processes. Current approaches for single cell clustering are often sensitive to the input parameters and have difficulty dealing with
Ming-Wen Hu, Dong Won Kim, Sheng Liu, Donald J Zack, Seth Blackshaw, Jiang Qian   +5 more
doaj   +1 more source

A rare case of metastatic small cell carcinoma of breast from mixed types of cervical carcinoma

Radiology Case Reports, 2022
Metastatic small cell carcinoma to the breast from the uterine cervix is an extremely rare case. We report a case of a 58-year-old postmenopausal woman who presented with postmenopausal bleeding.
Nur Asma Sapiai, MD, MMed (Rad), Fairos Abdul Muthalib, MD, MMed (RAd), Nurul Ain Mat Idris, MD, MMed, Zaitul Azra Mohd Nasir, MD   +3 more
doaj   +1 more source

Diffuse Large B-Cell Lymphoma Involvement in Two Different Localizations: A Case Report

The Surgery Journal, 2019
The genital system and skin involvement of diffuse B-cell lymphomas are quite rare. The appearance of these rare types in the same patient and the same period makes the treatment of the disease difficult. But both types respond well to anthracyclines and
Nilufer Bulut, Hılal Serap Arslan, Ipek Yıldız Ozaydın   +2 more
doaj   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti   +7 more
wiley   +1 more source

aKNNO: single-cell and spatial transcriptomics clustering with an optimized adaptive k-nearest neighbor graph

Genome Biology
Typical clustering methods for single-cell and spatial transcriptomics struggle to identify rare cell types, while approaches tailored to detect rare cell types gain this ability at the cost of poorer performance for grouping abundant ones.
Jia Li, Yu Shyr, Qi Liu
doaj   +1 more source

Natural killer cell T-cell lymphoma (nasal type), a rare and aggressive type of non-Hodgkin's lymphoma: Case report

Radiology Case Reports, 2023
In the sinonasal tract, diffuse large B-cell lymphomas are the predominant type non-Hodgkin's lymphoma while natural killer (NK) cell T-cell lymphoma, the nasal type, constitute only 3%-12% of NHLs in this region and is the more aggressive subtype. NK cell T-cell lymphoma mostly occurs in male at the median age of 50 years and has got a poor prognosis ...
Devraj Kandel, Shishan Dhakal, Sushila Thapa, Prakash Dhakal, Surendra Rayamajhi, Jagat Baniya   +5 more
openaire   +3 more sources

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source