Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins. [PDF]
Gulyás G +6 more
europepmc +1 more source
Targeting ICMT: A promising strategy in cancer treatment (Review). [PDF]
Hu J, Xiao Y, Tang J.
europepmc +1 more source
Synthetic gene circuits that selectively target RAS-driven cancers. [PDF]
Senn GV, Nissen L, Benenson Y.
europepmc +1 more source
How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization. [PDF]
Brock EJ +3 more
europepmc +1 more source
De novo design of Ras isoform selective binders. [PDF]
Zhang JZ +8 more
europepmc +1 more source
RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236. [PDF]
Pfeil AJ +16 more
europepmc +1 more source
An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases. [PDF]
Marcus K +3 more
europepmc +1 more source
Filamin A phosphorylation at S2152: a molecular switch fueling cancer and neurodegeneration. [PDF]
Burns LH, Romero A.
europepmc +1 more source

