Results 91 to 100 of about 2,867,834 (292)

KOMPSAT-3 Digital Elevation Model Correction Based on Point-to-Surface Matching

open access: yesRemote Sensing, 2019
In order to generate digital elevation models (DEMs) from high-resolution satellite images, the vendor-provided rational polynomial coefficients (RPCs) are commonly used.
Hyoseong Lee, Michael Hahn
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The rational points close to a curve II [PDF]

open access: yesActa Arithmetica, 2000
In the introduction to this paper, the author succinctly states the basic problem as follows: ``If a function \(f(x)\) takes values which are approximately rational at integer points or at rational points, is \(f(x)\) approximately a rational function?'' Alternatively, if \(f\) cannot be approximated over a long interval \([0,M]\) by a rational ...
openaire   +4 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Tensor product and irregularity for holonomic D-modules

open access: yes, 2015
To appear at C. R. Acad. Sci. ParisLet M be a complex of D-modules with bounded holonomic cohomology on a complex manifold.
Teyssier, Jean-Baptiste
core  

The behavior of rational points in families

open access: yes, 2019
A topic of current interest regards 'how often' a variety has a rational point. This topic was initially studied by Serre who gave upper bounds in the case of families of conics parametrised by a projective space.
Sofos, Efthymios
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

A Boundedness theorem for nearby slopes of holonomic D-modules

open access: yes, 2015
Using twisted nearby cycles, we define a new notion of slopes for complex holonomic D-modules. We prove a boundedness result for these slopes, study their functoriality and use them to characterize regularity.
Teyssier, Jean-Baptiste
core  

(G,F)-points on ℚ-algebraic varieties [PDF]

open access: yesNotes on Number Theory and Discrete Mathematics
Let ℚ be the field of rational numbers, and let C be an algebraically closed field containing ℚ. Let G ∈ ℚ[x,y,z] be a polynomial, then the zero set of G is Z(G) = {P ∈ Cⁿ | G(P) = 0}.
Yangcheng Li, Hongjian Li
doaj   +1 more source

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