Results 71 to 80 of about 159,936 (305)
Higher cotangent cohomology of rational surface singularities
, 2004 We give dimension formulas for the cotangent cohomology groups T^i for all rational surface singularities.
Stevens, Jan,
core +2 more sources
An Affine Model of a Riemann Surface Associated to a Schwarz–Christoffel Mapping
Axioms, 2021 In this paper, we construct an affine model of a Riemann surface with a flat Riemannian metric associated to a Schwarz–Christoffel mapping of the upper half plane onto a rational triangle.
Richard Cushman
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Rational Surfaces with Many Nodes [PDF]
Compositio Mathematica, 2002 We describe smooth rational projective algebraic surfaces over an algebraically closed field of characteristic different from 2 which contain $n \geq b_2-2$ disjoint smooth rational curves with self-intersection −2, where $b_2$ is the second Betti ...
DOLGACHEV I. +2 more
openaire +3 more sources
Wormholes and surface defects in rational ensemble holography
Journal of High Energy PhysicsWe study wormhole contributions to the bulk path integral in holographic models which are dual to ensembles of rational free boson conformal field theories.
Joris Raeymaekers, Paolo Rossi
doaj +1 more source
C1 rational quadratic trigonometric spline
Egyptian Informatics Journal, 2013 A Bézier like C1 rational quadratic trigonometric polynomial spline is developed. It defines two shape parameters in each subinterval. The approximation and geometric properties are investigated. The curvature continuity is established.
Maria Hussain, Sidra Saleem
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Zometool Rationalization of Freeform Surfaces [PDF]
IEEE Transactions on Visualization and Computer Graphics, 2014 An ever broader availability of freeform designs together with an increasing demand for product customization has lead to a rising interest in efficient physical realization of such designs, the trend toward personal fabrication. Not only large-scale architectural applications are (becoming increasingly) popular but also different consumer-level rapid ...
Henrik Zimmer, Leif Kobbelt
openaire +2 more sources
Modelling of microbial polyhydroxyalkanoate surface binding protein PhaP for rational mutagenesis
Microbial Biotechnology, 2017 Summary Phasins are unusual amphiphilic proteins that bind to microbial polyhydroxyalkanoate (PHA) granules in nature and show great potential for various applications in biotechnology and medicine.
Hongyu Zhao +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source