Results 1 to 10 of about 20,594 (125)
Genes influencing spinal bone mineral density in inbred F344, LEW, COP, and DA rats [PDF]
Functional & Integrative Genomics, 2009 Previously, we identified the regions of chromosomes 10q12-q31 and 15p16-q21 harbor quantitative trait loci (QTLs) for lumbar volumetric bone mineral density (vBMD) in female F2 rats derived from Fischer 344 (F344) x Lewis (LEW) and Copenhagen 2331 (COP) x Dark Agouti (DA) crosses.
Lixiang Liu +7 more
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Slc:Wistar outbred rats show close genetic similarity with F344 inbred rats
Experimental Animals, 2015 Although Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. We reported previously that nine genetic variations that were fixed in Slc:Wistar rats had identical genotypes in ...
Tadao Serikawa +3 more
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Inbred F344 rats as a biologic model of intra-abdominal sepsis
Brazilian Journal of Veterinary Research and Animal Science, 2002 Aiming to design a biologic model of acute intra-abdominal sepsis for experimental studies, conventional, isogenic rats F344 were infected with the bacteria Escherichia coli (E.coli), strain 11775, serotype H7:01:K1. Six hours after inoculation with E.
Damy, Sueli Blanes +5 more
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Frontiers in Neuroscience, 2018 The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark symptoms of human adult-onset HD.
Anne-Christine Plank +11 more
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Japanese Journal of Oral & Maxillofacial Surgery, 1991 A number of transplantable animal models of osteosarcoma have been developed so far, but the available strains of the rat that keep their bone-forming ability through many serial transplantations are limited both in the number of strains and their applicability.
S. Uchiyama
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The FASEB Journal, 2012 Genetic background has a major influence on the severity of renovascular disease. Previously we showed that Lewis rats with inducible hypertension caused by transgenic renin expression have lower blood pressure, higher renal plasma flow (RPF) and glomerular filtration rate (GFR) and are relatively protected from hypertensive renal microvascular injury ...
John J. Mullins +3 more
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The Journal of Immunology, 1971 Abstract The antibody response in the inbred rat is controlled by at least two autosomal genes; in addition, there is a sex influence which may include both additional genetic factors and environmental influences (1–3). We postulate that one of the major genes controlling the antibody response influences the size of the cell population ...
Thomas J Gill +3 more
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Frontiers in Behavioral Neuroscience, 2022 Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction ...
Silvia Corongiu +7 more
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Derivation of a germline competent transgenic Fischer 344 embryonic stem cell line. [PDF]
PLoS ONE, 2013 Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically ...
Hongsheng Men, Elizabeth C Bryda
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