Results 1 to 10 of about 22,238 (163)

Hi-C sequencing data from frontal cortex of laboratory rats [PDF]

Scientific Data
The three-dimensional structure of chromosomes is integral to nuclear organization and influences processes such as DNA replication, repair, and gene expression.
Panjun Kim, Rachel R. Ward, Burt M. Sharp, Robert W. Williams, Hao Chen   +4 more
doaj   +3 more sources

Photoperiodic Effects on Seasonal Physiology, Reproductive Status and Hypothalamic Gene Expression in Young Male F344 Rats [PDF]

Journal of neuroendocrinology, 2014
yesSeasonal or photoperiodically sensitive animals respond to altered day length with changes in physiology (growth, food intake and reproductive status) and behaviour to adapt to predictable yearly changes in the climate.
Barrett, Barrett, Braulke, Dardente, Francisco, Hanon, Hanon, Hau, Heideman, Heideman, Heideman, Helfer, Helfer, Herwig, Herwig, Hoffmann, Inestrosa, Klingenspor, Krol, Lobley, Nakane, Nakao, Nelson, Ono, Otsuka, Petri, Prendergast, Revel, Ross, Ross, Ross, Ross, Rousseau, Scherbarth, Seroka, Shaw, Shearer, Shoemaker, Togo, Tsai, Wallen, Wallen, Watanabe, Yasuo, Yoshimura   +44 more
core   +3 more sources

Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease

Frontiers in Neuroscience, 2018
The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark symptoms of human adult-onset HD.
Anne-Christine Plank, Fabio Canneva, Kerstin A. Raber, Yvonne K. Urbach, Julia Dobner, Maja Puchades, Jan G. Bjaalie, Clarissa Gillmann, Tobias Bäuerle, Olaf Riess, Hoa H. P. Nguyen, Stephan von Hörsten   +11 more
doaj   +2 more sources

Comparison of Thermal and Mechanical Pain Testing Modalities in Sprague Dawley and Fischer 344 Rats (<i>Rattus norvegicus</i>). [PDF]

Comp Med
While rodents are used extensively for studying pain, there is a lack of reported direct comparisons of thermal and mechanical pain testing methods in rats of different genetic backgrounds.
McNew JF, Davis DJ, Grimsrud KN, Bryda EC.   +3 more
europepmc   +2 more sources

Effect of chronic alcohol ingestion on the progression of periodontitis induced in Fisher-344 rats [PDF]

RGO: Revista Gaúcha de Odontologia, 2009
Objective: Understand the effect of chronic alcohol on the progression of periodontitis induced in Fischer-344 rats.Methods: For the study, 22 Fischer-344 rats, two months old were used, divided into groups: alcohol (n=8), ligature (n=7) and control (n=7)
Éder Ricardo Biasoli, Tereza Aparecida Delle Vedove Semenoff, Alex Semenoff Segundo   +2 more
doaj   +2 more sources

Influence of Age and Genetic Background on Ethanol Intake and Behavioral Response Following Ethanol Consumption and During Abstinence in a Model of Alcohol Abuse

Frontiers in Behavioral Neuroscience, 2022
Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction ...
Silvia Corongiu, Christian Dessì, Elena Espa, Augusta Pisanu, Annalisa Pinna, Daniele Lecca, Sandro Fenu, Cristina Cadoni   +7 more
doaj   +1 more source

Derivation of a germline competent transgenic Fischer 344 embryonic stem cell line. [PDF]

PLoS ONE, 2013
Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically ...
Hongsheng Men, Elizabeth C Bryda
doaj   +1 more source

Local vs. systemic administration of bisphosphonates in rat cleft bone graft: A comparative study. [PDF]

PLoS ONE, 2018
A majority of patients with orofacial cleft deformity requires cleft repair through a bone graft. However, elevated amount of bone resorption and subsequent bone graft failure remains a significant clinical challenge.
Christine Hong, Alison Quach, Lawrence Lin, Jeffrey Olson, Taewoo Kwon, Olga Bezouglaia, Jaime Tran, Michael Hoang, Kimberly Bui, Reuben H Kim, Sotirios Tetradis   +10 more
doaj   +1 more source

Experimental rat models of chronic allograft nephropathy: a review [PDF]

, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

Marker tolerant, immunocompetent animals as a new tool for regenerative medicine and long-term cell tracking

BMC Biotechnology, 2007
Background Immune-mediated rejection of labeled cells is a general problem in transplantation studies using cells labeled with any immunogenic marker, and also in gene therapy protocols.
Sandgren Eric P, Weber Karin, Unger Nina J, Odörfer Kathrin I, Erben Reinhold G   +4 more
doaj   +1 more source