Photoperiodic Effects on Seasonal Physiology, Reproductive Status and Hypothalamic Gene Expression in Young Male F344 Rats [PDF]
Seasonal or photoperiodically sensitive animals respond to altered day length with changes in physiology (growth, food intake and reproductive status) and behaviour to adapt to predictable yearly changes in the climate.
F. M. Tavolaro +4 more
semanticscholar +4 more sources
The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark symptoms of human adult-onset HD.
Anne-Christine Plank +11 more
doaj +2 more sources
Marker tolerant, immunocompetent animals as a new tool for regenerative medicine and long-term cell tracking [PDF]
Background Immune-mediated rejection of labeled cells is a general problem in transplantation studies using cells labeled with any immunogenic marker, and also in gene therapy protocols.
Sandgren Eric P +4 more
doaj +6 more sources
Inbred F344 rats as a biologic model of intra-abdominal sepsis [PDF]
Aiming to design a biologic model of acute intra-abdominal sepsis for experimental studies, conventional, isogenic rats F344 were infected with the bacteria Escherichia coli (E.coli), strain 11775, serotype H7:01:K1.
S. Damy +5 more
semanticscholar +4 more sources
Effects of neonatal handling on play and anxiety in F344 and Lewis rats
Play is an important part of normal childhood development and seen in many mammals, including rats. To better understand the interplay between genotype and postnatal experiences, the effects of neonatal handling on play were assessed in Lewis (LEW) and ...
S. Siviy
semanticscholar +3 more sources
Effect of chronic alcohol ingestion on the progression of periodontitis induced in Fisher-344 rats [PDF]
Objective: Understand the effect of chronic alcohol on the progression of periodontitis induced in Fischer-344 rats.Methods: For the study, 22 Fischer-344 rats, two months old were used, divided into groups: alcohol (n=8), ligature (n=7) and control (n=7)
Éder Ricardo Biasoli +2 more
doaj +2 more sources
Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction ...
Silvia Corongiu +7 more
doaj +1 more source
Derivation of a germline competent transgenic Fischer 344 embryonic stem cell line. [PDF]
Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically ...
Hongsheng Men, Elizabeth C Bryda
doaj +1 more source
Local vs. systemic administration of bisphosphonates in rat cleft bone graft: A comparative study. [PDF]
A majority of patients with orofacial cleft deformity requires cleft repair through a bone graft. However, elevated amount of bone resorption and subsequent bone graft failure remains a significant clinical challenge.
Christine Hong +10 more
doaj +1 more source
Experimental rat models of chronic allograft nephropathy: a review [PDF]
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core +2 more sources

