Results 1 to 10 of about 6,988 (81)

Population distribution profiles of the activities of blood alanine and aspartate aminotransferase in the normal F344 inbred rat by age and sex [PDF]

open access: yesLaboratory Animals, 1991
Data on the blood enzyme activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were collected from control male and female F344 rats participating in toxicity studies at 17, 30, 56, 80 and 106 weeks of age. The data were skewed to the right with significant deviation from normality.
Trevor Waner, A Nyska
exaly   +3 more sources

Slc:Wistar outbred rats show close genetic similarity with F344 inbred rats

open access: yesExperimental Animals, 2015
Although Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. We reported previously that nine genetic variations that were fixed in Slc:Wistar rats had identical genotypes in ...
Satoshi Nakanishi, Takashi Kuramoto
exaly   +4 more sources

Genes influencing spinal bone mineral density in inbred F344, LEW, COP, and DA rats [PDF]

open access: yesFunctional & Integrative Genomics, 2009
Previously, we identified the regions of chromosomes 10q12-q31 and 15p16-q21 harbor quantitative trait loci (QTLs) for lumbar volumetric bone mineral density (vBMD) in female F2 rats derived from Fischer 344 (F344) x Lewis (LEW) and Copenhagen 2331 (COP) x Dark Agouti (DA) crosses.
Imranul, Alam   +7 more
openaire   +2 more sources

Inbred F344 rats as a biologic model of intra-abdominal sepsis

open access: yesBrazilian Journal of Veterinary Research and Animal Science, 2002
Aiming to design a biologic model of acute intra-abdominal sepsis for experimental studies, conventional, isogenic rats F344 were infected with the bacteria Escherichia coli (E.coli), strain 11775, serotype H7:01:K1. Six hours after inoculation with E.
Damy, Sueli Blanes   +5 more
openaire   +3 more sources

Pressure–natriuretic and hemodynamic adjustments to chronic ACE inhibition in inbred F344 and Lewis rat strains

open access: yesThe FASEB Journal, 2012
Genetic background has a major influence on the severity of renovascular disease. Previously we showed that Lewis rats with inducible hypertension caused by transgenic renin expression have lower blood pressure, higher renal plasma flow (RPF) and glomerular filtration rate (GFR) and are relatively protected from hypertensive renal microvascular injury ...
Robert Ian Menzies   +3 more
openaire   +1 more source

Studies on transplantability of four strains of osteosarcoma in inbred F344 rats and successiveness of their bone-forming character.

open access: yesJapanese Journal of Oral & Maxillofacial Surgery, 1991
A number of transplantable animal models of osteosarcoma have been developed so far, but the available strains of the rat that keep their bone-forming ability through many serial transplantations are limited both in the number of strains and their applicability.
openaire   +2 more sources

Slc:Wistar outbred rats show close genetic similarity with F344 inbred rats

open access: yesSlc:Wistar outbred rats show close genetic similarity with F344 inbred rats
Although Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. We reported previously that nine genetic variations that were fixed in Slc:Wistar rats had identical genotypes in ...
openaire  

Inhalation of 1-bromopropane alters hippocampal expression of pathways related to immune system/inflammation and insulin signaling in experimental rats. [PDF]

open access: yesSci Rep
Huang F   +12 more
europepmc   +1 more source

Genome-wide association mapping and targeted loss of function studies identify <i>Shroom3</i> as a driver of hyperpolyploidy and ventricular dilation. [PDF]

open access: yesProc Natl Acad Sci U S A
Purdy AL   +18 more
europepmc   +1 more source

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