Results 31 to 40 of about 8,257 (145)

Effect of chronic alcohol ingestion on the progression of periodontitis induced in Fisher-344 rats [PDF]

RGO: Revista Gaúcha de Odontologia, 2009
Objective: Understand the effect of chronic alcohol on the progression of periodontitis induced in Fischer-344 rats.Methods: For the study, 22 Fischer-344 rats, two months old were used, divided into groups: alcohol (n=8), ligature (n=7) and control (n=7)
Éder Ricardo Biasoli, Tereza Aparecida Delle Vedove Semenoff, Alex Semenoff Segundo   +2 more
doaj  

The effects of cocaine self-administration on dendritic spine density in the rat hippocampus are dependent on genetic background [PDF]

, 2015
Chronic exposure to cocaine induces modifications to neurons in the brain regions involved in addiction. Hence, we evaluated cocaine-induced changes in the hippocampal CA1 field in Fischer 344 (F344) and Lewis (LEW) rats, 2 strains that have been widely ...
Ambrosio, Emilio, Ballesteros-Yañez, Inmaculada, Coria, Santiago M., Felipe Oroquieta, Javier de, Kastanauskaite, Asta, Miguens Vázquez, Miguel, Selvas, Abraham   +6 more
core   +2 more sources

Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity. [PDF]

, 2016
Severe, repeated or chronic stress produces negative health outcomes including disruptions of the sleep/wake cycle and gut microbial dysbiosis. Diets rich in prebiotics and glycoproteins impact the gut microbiota and may increase gut microbial species ...
Berg, Brian M, Chichlowski, Maciej, Fleshner, Monika, Greenwood, Benjamin N, Knight, Rob, Mika, Agnieszka, Roller, Rachel, Thompson, Robert S   +7 more
core   +1 more source

Identification of a Novel Gene for Diabetic Traits in Rats, Mice, and Humans [PDF]

, 2014
The genetic basis of type 2 diabetes remains incompletely defined despite the use of multiple genetic strategies. Multiparental populations such as heterogeneous stocks (HS) facilitate gene discovery by allowing fine mapping to only a few megabases ...
Andrae, Jaime Wendt, Galione, Antony, He, Hong, Hessner, Martin, Hoffmann, Raymond G., Holl, Katie, Jacob, Howard, Jia, Shuang, Kaldunski, Mary, Li, Shun-Hua, Meigs, James, Parrington, John, Ruas da Silva, Margarida, Simpson, Pippa, Solberg Woods, Leah C., Stoddard, Alex, Tsaih, Shirng-Wern, Tschannen, Michael, Wiederhold, Andrew   +18 more
core   +1 more source

Expression of an anti-CD4 single-chain antibody fragment from the donor cornea can prolong corneal allograft survival in inbred rats [PDF]

, 2012
To investigate whether expression of an anti-CD4 antibody fragment (scFv) by a lentivector-transduced donor cornea can prolong rat corneal allograft survival.
Appleby, Sarah Louise, Brereton, Helen Mary, Coster, Douglas John, Jessup, Claire Frances, Kirk, Kirsty, Mortimer, Lauren A, Tan, Chuan K, Williams, Keryn Anne   +7 more
core   +1 more source

Effects of Amphetamine on Striatal Dopamine Release, Open-Field Activity, and Play in Fischer 344 and Sprague–Dawley Rats

, 2015
Previous work from our laboratories has shown that juvenile Fischer 344 (F344) rats are less playful than other strains and also appear to be compromised in dopamine (DA) functioning.
Akopian, Garnik, Eck, Samantha R., McDowell, Lana S., Siviy, Stephen M., Turano, Alexandra, Walsh, John P.   +5 more
core   +1 more source

Effect of photoperiodicity in the pregnancy rate of isogenic rats (F344) [PDF]

, 2011
O uso de animais isogênicos apresenta grandes vantagens experimentais, como uniformidade fenotípica e genotípica (reduzindo o número de animais em experimentos) e histocompatibilidade, permitindo, assim, o acúmulo de informações e a repetibilidade dos ...
Alves, Alexandre José, Alves, Flávio Ribeiro, Baptista, Alexandre Bastos, Ferreira, Amanda Olivotti, Guerra, Ricardo Romão, Miglino, Maria Angélica, Morita, Erika Lissa, Passos, Cristiane Carlin   +7 more
core   +2 more sources

High-resolution genome screen for bone mineral density in heterogeneous stock rat [PDF]

, 2014
We previously demonstrated that skeletal mass, structure, and biomechanical properties vary considerably in heterogeneous stock (HS) rat strains. In addition, we observed strong heritability for several of these skeletal phenotypes in the HS rat model ...
Alam, Imranul, Baud, Amelie, Blázquez, Gloria, Cañete, Toni, Dieze, Margarita, Díaz-Morán, Sira, Econs, Michael J., Fernández-Teruel, Alberto, Foroud, Tatiana, Johannesson, Martina, Koller, Daniel L., López-Aumatell, Regina, Martínez-Membrives, Esther, Olsson, Tomas, Stridh, Pernilla, Tobeña, Adolf   +15 more
core   +1 more source

Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats

Aging Cell, Volume 24, Issue 8, August 2025.
Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura, Csaba Kerepesi, Juliet Polok Sarkar, Ferenc Torma, Zoltan Bori, Lei Zhou, Peter Bakonyi, Attila Kolonics, Laszlo Balogh, Mitsuru Higuchi, Vivien Pillár, Karolina Pircs, Lauren Gerard Koch, Steven Loyal Britton, Erika Koltai, Zsolt Radak   +15 more
wiley   +1 more source

Oxidative Stress in People Living With HIV: Are Diverse Supplement Sources the Solution?

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aim Antiretroviral therapy (ART) has reduced human immunodeficiency virus (HIV)/AIDS to a manageable chronic condition even though no cure exists. Despite ART control, latent HIV infection results in failed memory CD4 T‐cell responses, immune overactivation, inflammation, oxidative stress, genomic instability, deoxyribonucleic ...
Esimebia Adjovi Amegashie, Ruth Oyawole Sikeola, Emmanuel Ayitey Tagoe, Elijah Paintsil, Kwasi Torpey, Osbourne Quaye   +5 more
wiley   +1 more source