Results 21 to 30 of about 5,780 (131)

Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]

, 1989
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone, A.L. Hoffman, B.F. Banner, Barclay A, Berenson R J, Beschorner W E, Bril H, D.G. Sheahan, D.V. Cramer, Dallman M J, Elkins W L, Farnsworth A, Filipovich A H, Kvalheim G, L. Makowka, Lubaroff D M, Martin P J, Monchik G J, Oaks M K, P. Rettinger, Prentice H G, Reisner Y, Rodt H, Slavin R E, T.E. Starzl, Thtschka P J, Tsoi M-S, Van Bekkum D W, Vartdal F, Waldman H, X. Cai   +30 more
core   +1 more source

The effects of cocaine self-administration on dendritic spine density in the rat hippocampus are dependent on genetic background [PDF]

, 2015
Chronic exposure to cocaine induces modifications to neurons in the brain regions involved in addiction. Hence, we evaluated cocaine-induced changes in the hippocampal CA1 field in Fischer 344 (F344) and Lewis (LEW) rats, 2 strains that have been widely ...
Ambrosio, Emilio, Ballesteros-Yañez, Inmaculada, Coria, Santiago M., Felipe Oroquieta, Javier de, Kastanauskaite, Asta, Miguens Vázquez, Miguel, Selvas, Abraham   +6 more
core   +2 more sources

A Neonatal Nurse‐Controlled Model of Analgesia to Manage Post‐Operative Pain in the Surgical Neonate: A Pilot Randomised Controlled Trial

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To test the feasibility and acceptability of a newly developed model of neonatal nurse‐controlled analgesia to manage pain in the post‐operative infant. Design The study utilised a single‐centre two‐arm parallel, unblinded randomised controlled external pilot trial design.
Renee Muirhead, Kathryn Kynoch, Glenda Hawley, Emma Ballard, Pita Birch, P. A. Lewis   +5 more
wiley   +1 more source

Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine. [PDF]

, 1987
In rats, FK significantly prolonged heterotopic heart graft survival over a wide dose range when given for 2 weeks starting on the day of the operation.
Chapman, F, Lai, HS, Lee, PH, Makowka, L, Murase, N, Nalesnik, MA, Starzl, TE, Todo, S   +7 more
core  

Platelet-activating factor and hyperacute rejection: The effect of a platelet-activating factor antagonist, sri 63-441, on rejection of xenografts and allografts in sensitized hosts [PDF]

, 1990
The pathogenesis of hyperacute transplantation reactions includes the activation of a cascade of nonspecific inflammatory reactions that precipitates the destruction of the target organ.
Chapman, FA, Cramer, DV, Makowka, L, Qian, S, Starz, TE, Sun, H   +5 more
core   +1 more source

Maternal Provisioning of Offspring With Defence Chemicals in a Facultatively Parthenogenetic Stick Insect

Ecology and Evolution, Volume 15, Issue 4, April 2025.
We show that females of the stick‐insect Megacrania batesii transfer defensive alkaloids to their offspring, providing a novel example of maternal provisioning. We also provide evidence that provisioning is enhanced by parthenogenetic reproduction in this species.
Ana Caroline Oliveira Vasconcelos, Lewis Adler, Russell Bonduriansky   +2 more
wiley   +1 more source

A novel small molecule phagocytosis inhibitor, KB‐208, ameliorates ITP in mouse models with similar efficacy as IVIG

Transfusion, Volume 64, Issue 12, Page 2233-2240, December 2024.
Abstract Background The characteristic feature of immune cytopenias involves the process of extravascular phagocytosis, wherein macrophages in the spleen and/or liver engage in the destruction of blood cells that have been opsonized by auto‐ or alloantibodies.
Melika Loriamini, Melissa M. Lewis‐Bakker, Beth Binnington, Lakshmi P. Kotra, Donald R. Branch   +4 more
wiley   +1 more source

LC–MS‐Based Simultaneous Determination of Biomarkers in Dried Urine Spots for the Detection of Cofactor‐Dependent Metabolic Disorders in Neonates

Journal of Separation Science, Volume 47, Issue 22, November 2024.
ABSTRACT Deficiency of cofactors for various enzymes can lead to inborn errors of metabolism. These conditions frequently occur as seizures, which lead to permanent brain damage. Newborn screening for biomarkers associated with these disorders can help in early detection and treatment.
Arya Raveendran, Ashutosh Gupta, Leslie E. Lewis, Krishnananda Prabhu, Sudheer Moorkoth   +4 more
wiley   +1 more source

Induction of donor-specific transplantation tolerance to skin and cardiac allografts using mixed chimerism in (A + B → A) in rats [PDF]

, 1993
Mixed allogeneic chimerism (A + B → A) was induced in rats by reconstitution of lethally irradiated LEW recipients with a mixture of T-cell depleted (TCD) syngeneic and TCD allogeneic ACI bone marrow. Thirty-seven percent of animals repopulated as stable
Cai, X, Fung, JJ, Markus, PM, Selvaggi, G, Starzl, TE   +4 more
core   +1 more source

Re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives

EFSA Journal, Volume 22, Issue 11, November 2024.
Abstract This opinion deals with the re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives. Saccharin is the chemically manufactured compound 1,2‐benzisothiazol‐3(2H)‐one‐1,1‐dioxide. Along with its sodium (Na), potassium (K) and calcium (Ca) salts, they are authorised as sweeteners (E 954).
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Reginald FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Monika Batke, Ellen Bruzell, James Chipman, Karlien Cheyns, Riccardo Crebelli, Cristina Fortes, Peter Fürst, Thorhallur Halldorsson, Jean‐Charles LeBlanc, Manuela Mirat, Oliver Lindtner, Alicja Mortensen, Evangelia Ntzani, Romina Shah, Heather Wallace, Matthew Wright, Stefania Barmaz, Consuelo Civitella, Petra Georgelova, Federica Lodi, Elena Mazzoli, Josef Rasinger, Ana Maria Rincon, Alexandra Tard, Panagiota Zakidou, Maged Younes   +42 more
wiley   +1 more source