Results 21 to 30 of about 49,631 (197)
Genetic Factors in Animal Models of Intestinal Inflammation
The critical importance of host genetic susceptibility in determining chronicity, aggressiveness and complications of intestinal inflammation is clearly demonstrated by studies of inbred rodents, transgenic rats and spontaneous mutants. Inbred Lewis rats
R Balfour Sartor
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Comparison of voluntary ethanol intake by two pairs of rat lines used as genetic models of anxiety
The relationship between anxiety-related behaviors and voluntary ethanol intake was examined in two pairs of rat lines by the oral ethanol self-administration procedure. Floripa high (H) and low (L) rats selectively bred for contrasting anxiety responses
G.E. Da Silva, A. Ramos, R.N. Takahashi
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Behavioral profile predicts ethanol preference in adolescent mice, but not in adults: A machine learning approach. [PDF]
The present study reveals that adolescent behavioral phenotypes strongly predict ethanol preference in mice, while no predictive patterns emerged in adulthood. Machine learning analysis identified sucrose preference as a positive predictor and sociability as a negative predictor of alcohol intake, highlighting natural reward sensitivity and social ...
Portugal LCL +8 more
europepmc +2 more sources
Identifying predictors of activity based anorexia susceptibility in diverse genetic rodent populations. [PDF]
Animal studies are very useful in detection of early disease indicators and in unravelling the pathophysiological processes underlying core psychiatric disorder phenotypes.
Eneda Pjetri +9 more
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Rodents are known to display fear-related responses when exposed to the odor of natural predators, such as cats, even when they are totally naïve to these stimuli.
Ramos André +2 more
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The current report assessed the effects of low-level proton irradiation in inbred adult male Fischer 344 and Lewis rats performing an analog of the human Psychomotor Vigilance Test (PVT), commonly utilized as an object risk assessment tool to quantify ...
Catherine M Davis +2 more
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We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren +6 more
wiley +1 more source
Multimorbidity and animal models
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang +7 more
wiley +1 more source
Currently, the animals commonly used to establish animal models of benign airway stenosis (BAS) include mice, rats, pigs, dogs, rabbits, and ferrets. The establishment methods involve one or a combination of two methods such as mechanical injury, tracheal cautery, cuff overpressure intubation, laser injury, and endoscopic silver nitrate cauterization ...
Wusheng Zhang +6 more
wiley +1 more source

