Results 21 to 30 of about 97,044 (222)

Worm burdens in outbred and inbred laboratory rats with morphometric data on Syphacia muris (Yamaguti, 1935) Yamaguti, 1941 (Nematoda, Oxyuroidea)

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
Syphacia muris worm burdens were evaluated in the rat Rattus norvegicus of the strains Wistar (outbred), Low/M and AM/2/Torr (inbred), maintained conventionally in institutional animal houses in Brazil. Morphometrics and illustration data for S.
Roberto Magalhães Pinto   +3 more
doaj   +1 more source

Genetic Factors in Animal Models of Intestinal Inflammation

open access: yesCanadian Journal of Gastroenterology, 1995
The critical importance of host genetic susceptibility in determining chronicity, aggressiveness and complications of intestinal inflammation is clearly demonstrated by studies of inbred rodents, transgenic rats and spontaneous mutants. Inbred Lewis rats
R Balfour Sartor
doaj   +1 more source

Comparison of voluntary ethanol intake by two pairs of rat lines used as genetic models of anxiety

open access: yesBrazilian Journal of Medical and Biological Research, 2004
The relationship between anxiety-related behaviors and voluntary ethanol intake was examined in two pairs of rat lines by the oral ethanol self-administration procedure. Floripa high (H) and low (L) rats selectively bred for contrasting anxiety responses
G.E. Da Silva, A. Ramos, R.N. Takahashi
doaj   +1 more source

Identifying predictors of activity based anorexia susceptibility in diverse genetic rodent populations. [PDF]

open access: yesPLoS ONE, 2012
Animal studies are very useful in detection of early disease indicators and in unravelling the pathophysiological processes underlying core psychiatric disorder phenotypes.
Eneda Pjetri   +9 more
doaj   +1 more source

Genetic differences in the development of physical dependence on pentobarbital in four inbred strains of rats.

open access: yesJapanese Journal of Pharmacology, 1987
Fischer 344 (F344), Lewis (LEW), spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats were chronically fed food containing pentobarbital on an escalating drug dosage schedule over a period of 47 days.
T. Suzuki   +4 more
semanticscholar   +1 more source

Two inbred rat strains contrasting for anxiety-related behaviors show similar levels of defensive responses to cat odor

open access: yesBehavioral and Brain Functions, 2007
Rodents are known to display fear-related responses when exposed to the odor of natural predators, such as cats, even when they are totally naïve to these stimuli.
Ramos André   +2 more
doaj   +1 more source

Deficits in Sustained Attention and Changes in Dopaminergic Protein Levels following Exposure to Proton Radiation Are Related to Basal Dopaminergic Function.

open access: yesPLoS ONE, 2015
The current report assessed the effects of low-level proton irradiation in inbred adult male Fischer 344 and Lewis rats performing an analog of the human Psychomotor Vigilance Test (PVT), commonly utilized as an object risk assessment tool to quantify ...
Catherine M Davis   +2 more
doaj   +1 more source

The effects of buprenorphine on behaviour in the ACI and BN rat inbred strains [PDF]

open access: yesLaboratory Animals, 2008
Summary Buprenorphine is a partial μ, κ agonist that has been shown to influence spontaneous behaviour in animals. Previously, we have demonstrated significant differences in the analgesic response to buprenorphine between the August Copenhagen Irish (ACI)/SegHsd and the Brown Norway (BN)/RijHsd inbred rat strains.
Avsaroglu, H.   +4 more
openaire   +5 more sources

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li   +8 more
wiley   +1 more source

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