Results 61 to 70 of about 53,463 (191)
Early life stress is associated with an increased risk of alcohol use disorder and posttraumatic stress disorder. We previously used an infant footshock model in rats that produces increases in fear learning and alcohol drinking to explore this shared predisposition.
Thomas W. Perry+9 more
wiley +1 more source
Lymphoma caused by intestinal microbiota. [PDF]
The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core +2 more sources
Normal spatial learning and improved spatial working memory in mice (mus musculus) lacking dopamine d4 receptors [PDF]
Dopamine terminals in the hippocampus and prefrontal cortex modulate cognitive processes such as spatial learning and working memory. Because dopamine D4 receptors are expressed in these brain areas we have analyzed mutant mice lacking this receptor ...
Avale, Maria Elena+3 more
core +1 more source
Phenotypic Variation in Strength Among Eleven Inbred Strains of Rats
As a first step toward the long-range goal of identifying the genes that determine strength, we subjected 11 inbred strains of rats to three tests of muscular strength. The tests consisted of measuring (1) the force exerted by the rat as it was pulled by the base of the tail off a grid on the pan of a top-loading electronic balance (scale test); (2 ...
Lauren G. Koch+4 more
openaire +3 more sources
Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa+2 more
wiley +1 more source
Heterogeneity of the gut microbiome in mice : guidelines for optimizing experimental design [PDF]
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human ...
Brinkman, Brigitta+4 more
core +1 more source
Abstract Aim A study reported that therapeutic hypothermia (TH) did not reduce the combined prognosis of mortality and disability at 18 months, in low‐ and middle‐income countries for patients with hypoxic ischaemic encephalopathy (HIE) who received TH, suggesting its no implementation in these regions.
Carlos Fajardo+7 more
wiley +1 more source
Adropin: An endocrine link between the biological clock and cholesterol homeostasis [PDF]
This article explores two translation models circling around the key issue “equivalence” in translation studies. They are the Jerome Model and the Horace Model. They differentiate from each other in the aspects of the translating priorities and purposes,
Rao, D. C, et al,
core +3 more sources
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett+4 more
wiley +1 more source
Genome-Wide Fine-Mapping Of Diabetic Traits [PDF]
Type 2 diabetes results from both genes and the environment. Mapping genetic loci in animal models can help identify genes that are involved in type 2 diabetes to better understand the disease.
Baur, Brittany
core +1 more source