Results 71 to 80 of about 129,705 (270)

Shear Stress Is Differentially Regulated Among Inbred Rat Strains [PDF]

Circulation Research, 2003
An important compensatory response to atherosclerosis is vascular remodeling, with maintenance of vessel lumen diameter and shear stress. Both hemodynamic and environmental factors contribute to vascular remodeling and shear stress regulation, and the process is probably also influenced by genetic factors.
Jody K. Miyashiro, Bradford C. Berk, Jamila Ibrahim   +2 more
openaire   +3 more sources

Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena. [PDF]

, 2013
Adult male mice emit large number of complex ultrasonic vocalizations (USVs) when interacting with adult females. Call numbers and call categories differ greatly among inbred mouse strains.
Crawley, Jacqueline N, Kalikhman, David, Loureiro, Darren, Yang, Mu   +3 more
core   +2 more sources

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism [PDF]

, 2013
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research.
A Gozzi, A Gozzi, A Gozzi, A Gozzi, A Gozzi, AA Turk, AC Stanfield, AE Dorr, Alberto Galbusera, Alessandro Gozzi, Allan V. Kalueff, Angelo Bifone, AY Hardan, AY Hardan, B Avants, BA Babineau, BB Avants, BB Avants, BB Avants, BU Meye, D Badaruddin, D Wahlsten, D Wahlsten, E Anagnostou, F Tovar-Moll, G Zaharchuk, H Ito, H Utsunomiya, J Ashburner, J Ellegood, JL Silverman, JL Silverman, JL Silverman, JL Whitwell, JM Mountz, JP Lerch, JP Lerch, KL Hyde, L Ferrari, L Ferrari, LK Paul, LK Paul, Luca Dodero, M Magnuson, M Sasaki, M Wohr, M Yang, M Yang, M Yang, M Zilbovicius, MA Just, Maria Luisa Scattoni, Mario Damiano, ME Vissers, ML Scattoni, ML Senjem, MM Haznedar, MM Haznedar, MS George, N Boddaert, N Hadjikhani, O Devinsky, R Adolphs, R Via E, RG Gonzalez, RJ Zatorre, S Mori, S Schobel, S Shen, SM Smith, Sotirios A. Tsaftsaris, SR Das, SS Moy, SS Moy, T Ohnishi, T Ren, TW Frazier, VJ Bolivar, WS Brown   +78 more
core   +6 more sources

Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency.

PLoS Genetics, 2019
Recent evidence implicates mononuclear diploid cardiomyocytes as a proliferative and regenerative subpopulation of the postnatal heart. The number of these cardiomyocytes is a complex trait showing substantial natural variation among inbred mouse strains
Peiheng Gan, Michaela Patterson, Alexa Velasquez, Kristy Wang, Di Tian, Jolene J Windle, Ge Tao, Daniel P Judge, Takako Makita, Thomas J Park, Henry M Sucov   +10 more
doaj   +1 more source

Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]

, 2013
Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core   +1 more source

Management and Modification of Flavonoids Against Nonalcoholic Fatty Liver Disease

Food Bioengineering, EarlyView.
Flavonoids protect against NAFLD by enhancing mitochondrial function, reducing ER stress, and modulating gut microbiota. Structural modifications improve flavonoid efficacy, offering a promising dietary strategy for NAFLD management. ABSTRACT Flavonoids are small bioactive molecules commonly found in plant‐derived foods, exhibiting antioxidant, anti ...
Weidong Bai, Bingqi Huang, Wenhong Zhao, Gongliang Liu, Limei Yu, Zhi Lu, Hong Wang   +6 more
wiley   +1 more source

Derivation of a germline competent transgenic Fischer 344 embryonic stem cell line. [PDF]

PLoS ONE, 2013
Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically ...
Hongsheng Men, Elizabeth C Bryda
doaj   +1 more source

Scalable Purification of Iron Oxide Nanoparticles for Organ Cryopreservation and Transplantation

Small, EarlyView.
Scalable purification of silica‐coated iron oxide nanoparticles (sIONP) enables organ‐scale nanowarming and cryopreservation. Tangential flow filtration (TFF) offers a rapid and scalable alternative to conventional ultracentrifugation, completing purification in 2.5 h.
Onyinyechukwu Justina Oziri, Joseph Sushil Rao, Cameron Scheithauer, Zonghu Han, Saurin Kantesaria, Diane Tobolt, Haopu Liang, Michael L Etheridge, Yadong Yin, Erik B Finger, John C Bischof   +10 more
wiley   +1 more source

Genetical genomic determinants of alcohol consumption in rats and humans

BMC Biology, 2009
Background We have used a genetical genomic approach, in conjunction with phenotypic analysis of alcohol consumption, to identify candidate genes that predispose to varying levels of alcohol intake by HXB/BXH recombinant inbred rat strains.
Mangion Jonathan, Pravenec Michal, Hübner Norbert, Heinig Matthias, Bell Richard L, Kechris Katerina, Richardson Heather N, Koob George, Goldman David, Hodgkinson Colin, Flodman Pam, Printz Morton, Saba Laura, Tabakoff Boris, Legault Lucie, Dongier Maurice, Conigrave Katherine M, Whitfield John B, Saunders John, Grant Bridget, Hoffman Paula L   +20 more
doaj   +1 more source