Results 81 to 90 of about 49,631 (197)

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

G3: Genes, Genomes, Genetics, 2016
To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (
Pamela J. Kaisaki, Georg W. Otto, Karène Argoud, Stephan C. Collins, Robert H. Wallis, Steven P. Wilder, Anthony C. Y. Yau, Christophe Hue, Sophie Calderari, Marie-Thérèse Bihoreau, Jean-Baptiste Cazier, Richard Mott, Dominique Gauguier   +12 more
doaj   +1 more source

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang   +8 more
wiley   +1 more source

The ZmFKF1b‐ZmDi19‐5 Regulatory Module Coordinates Drought Tolerance and Flowering Time in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought is a major environmental stress that inhibits plant growth and reduces crop yields. The Di19 gene family is known to play a pivotal role in mediating plant responses to drought. However, the mechanisms by which Di19 proteins integrate drought response with developmental processes, particularly flowering time, remain largely unknown in ...
Haixia Zeng, Dandan Dou, Yang Yang, Yan Yan, Yawen Sun, Shuhan Yang, Wen Yao, Shifang Zhao, Mingle Wang, Zhixue Liu, Zhenzhen Ren, Huihui Su, Liru Cao, Lixia Ku, Xu Zheng, Chengwei Li, Yanhui Chen   +16 more
wiley   +1 more source

Genome‐Wide Association Study Reveals the Genetic Architecture and Key Drought and Yield Related Genes in Common Vetch (Vicia sativa L.)

Plant Biotechnology Journal, EarlyView.
ABSTRACT Common vetch (Vicia sativa L.) is one of the most economically important annual pasture legumes worldwide. Many factors affect the yield of common vetch; however, the genetic architecture and gene functions associated with common vetch yield have not been explored. On the basis of 115.53 million single‐nucleotide polymorphisms (SNPs) and 18.55
Wenxian Liu, Xianglong Zhao, Yanpeng Li, Qiang Zhou, Iain R. Searle, Wengang Xie, Zhibiao Nan, Zhipeng Liu   +7 more
wiley   +1 more source

Estrogen-Dependent Upregulation of Adcyap1r1 Expression in Nucleus Accumbens Is Associated With Genetic Predisposition of Sex-Specific QTL for Alcohol Consumption on Rat Chromosome 4

Frontiers in Genetics, 2018
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more than ...
John Paul Spence, Jill L. Reiter, Bin Qiu, Hao Gu, Dawn K. Garcia, Lingling Zhang, Tamara Graves, Kent E. Williams, Paula J. Bice, Yi Zou, Zhao Lai, Weidong Yong, Tiebing Liang   +12 more
doaj   +1 more source

The Zma‐miRNA319‐ZmMYB74 Module Regulates Maize Resistance to Stalk Rot Disease by Modulating Lignin Deposition

Plant Biotechnology Journal, EarlyView.
ABSTRACT Stalk rot, primarily caused by Fusarium graminearum (Fg) and Pythium inflatum (Pi), is a major maize disease responsible for significant yield losses. The molecular mechanisms governing defence against these pathogens remain poorly understood. To uncover key miRNAs and their regulatory genes, small RNA, degradome, and transcriptome sequencing ...
Yanyong Cao, Juan Ma, Zeqiang Cheng, Laikun Xia, Lifeng Wang, Jingjing Li, Xingrui Zhang, Shengbo Han, Yan‐Ping Tian, Mingjun Li, Zhanyuan Zhang, Jihua Tang, Zaifeng Fan, Tao Zhou, Canxing Duan, Xiang‐Dong Li, Huiyong Li   +16 more
wiley   +1 more source

Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Electrocardiographic (ECG) parameters are regarded as intermediate phenotypes of cardiac arrhythmias. Insight into the genetic underpinnings of these parameters is expected to contribute to the understanding of cardiac arrhythmia mechanisms ...
Michiel E. Adriaens, Elisabeth M. Lodder, Aida Moreno‐Moral, Jan Šilhavý, Matthias Heinig, Charlotte Glinge, Charly Belterman, Rianne Wolswinkel, Enrico Petretto, Michal Pravenec, Carol Ann Remme, Connie R. Bezzina   +11 more
doaj   +1 more source

Developing an Efficient System for Hybrid Rice Seed Production Using Partial Male Sterility

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient production of hybrid rice seeds requires male sterility systems to overcome the challenges of self‐pollination. In this study, we identified male gametic transfer defect (GTrD)5 and GTrD9 as essential genes for the process of male gamete transmission in rice.
Su‐Kyoung Lee, Woo‐Jong Hong, Eui‐Jung Kim, Choonseok Lee, Sunok Moon, Sun‐Hwa Ha, Ki‐Hong Jung   +6 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source