The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Mesenchymal stem cells (MSCs) have been shown to enhance tissue regeneration and wound healing. This preclinical study investigated the therapeutic potential of human bone marrow‐derived mesenchymal stem cells (hBM‐MSCs) for accelerating diabetic wound healing.
Rong‐Fu Chen +5 more
wiley +1 more source
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
Associations Between Gut Microbiota and Tissue Exposure of <i>Gastrodia elata</i>-Derived Bioactive Components: Observations from Fecal Microbiota Transplantation in SHRs and Wistar Rats. [PDF]
Pharmaceuticals (Basel)Wang X, Huang M, Xu X.
europepmc +1 more source
Optimization of Gradient Pulse Shape Prediction Using Temporal Convolutional Networks
Magnetic Resonance in Medicine, EarlyView.Purpose To improve TCN‐based gradient‐waveform prediction with respect to acquisition efficiency and inference speed, and to evaluate its use for radial imaging. Methods Gradient waveforms were measured using a thin‐slice method on a preclinical MRI system. Separate TCN models were trained for each physical gradient axis to predict both gradient and B0$
Jiří Vitouš +2 more
wiley +1 more source
[Hereditary folate malabsorption due to an SLC46A1 mutation with cerebral folate deficiency and refractory epilepsy: first case reported in Argentina] [PDF]
Rev Fac Cien Med Univ Nac CordobaGrosso CL +6 more
europepmc +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Protective Effects of Lactobacillus-Derived Probiotics and Postbiotics on Renal and Reproductive Function in Escherichia coli-Infected Rats. [PDF]
Vet Med SciSedghi S, Keshtmand Z, Hosseini S.
europepmc +1 more source
Neuroprotection, EarlyView.This systematic review and meta‐analysis assessed the cytoprotective effects of neuromodulation in preclinical models of ischemic stroke. Pooled analyses showed that neuromodulation significantly reduced infarct volume and improved neurological outcomes.
Igor Caitano Salles +7 more
wiley +1 more source
Phytotherapy Research, EarlyView.Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia +6 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source