Results 201 to 210 of about 342,681 (291)

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats. [PDF]

Nat Commun
Song R, Lin Y, Zhang M, Liu Z, Zhang R, Zhao J, Li B.   +6 more
europepmc   +1 more source

Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration

Small Science, EarlyView.
Solvent transfer‐induced phase separation transforms bioinert polyethylene glycol diacrylate into bioactive scaffolds featuring bicontinuous interconnected porosity, with negative Gaussian curvature, and unique topographical patterning. These attributes enable stem cell attachment, proliferation, and differentiation without basement membrane matrix ...
Aihik Banerjee, Anjana Khanal, Prince D. Okoro, Shankar P. Kharal, Kevin Dalsania, Baishali Kanjilal, Shiril B. Iragavarapu, Yiqing Chen, Janitha M. Unagolla, Huinan H. Liu, Joshua T. Morgan, Robert P. Hesketh, Arash Pezhouman, Reza Ardehali, Bahman Anvari, Martin F. Haase, Iman Noshadi   +16 more
wiley   +1 more source

Impairment of Spatial Working Memory but Preservation of Recognition Memory in Female Rats with Spontaneous Absence Seizures. [PDF]

Neurochem Res
Neuparth-Sottomayor M, Morais TP, Good M, Sebastião AM, Di Giovanni G, Crunelli V, Vaz SH.   +6 more
europepmc   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

Small Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang, Yifan Ma, Yutong Liu, Shiyan Dong, Michelle Najarro Torres, Betty Y.S. Kim, Changsheng Liu, Lili Sun, Yuan Yuan, Wen Jiang   +9 more
wiley   +1 more source

Monosodium glutamate exacerbated the lipopolysaccharide-induced reproductive toxicity of male Wistar rats. [PDF]

BMC Pharmacol Toxicol
Ogunro OB, Asejeje FO, Hamzat ZO.
europepmc   +1 more source

Cadmium‐Induced Mitochondrial and MAMs Dysregulation in Rat Testis: The Protective Role of D‐Aspartate

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd), a heavy metal, disrupts the structure of seminiferous tubules and induces cell death at multiple stages of sperm development. Cd also impairs Leydig cells (LCs), resulting in reduced serum testosterone (T) levels. This study primarily examined the impact of Cd on the mitochondrial compartment and mitochondrial‐associated ...
Debora Latino, Sara Falvo, Massimo Venditti, Alessandra Santillo, Giulia Grillo, Gabriella Chieffi Baccari, Imed Messaoudi, Maria Maddalena Di Fiore   +7 more
wiley   +1 more source

Retinal Pigment Epithelium-Targeting Gene Therapy Corrects Ocular Symptoms in Mouse and Rat Models of Oculocutaneous Albinism Type I. [PDF]

MedComm (2020)
Song L, Ren C, Luo M, Su J, Jin X, Fu J, Xu Q, Wu X, Liu F, Ye Q, Hu M, Liu M, Li Q, An Y, Li M, Wang Q, She K, Lu F, Yang Y.   +18 more
europepmc   +1 more source

Ecotoxicological Evaluation of the Antimicrobial Butylparaben in Edaphic Organisms Using Multiple Biomarkers

Environmental Toxicology, EarlyView.
ABSTRACT Butylparaben (BuP) recurrently contaminates soils worldwide, mainly by incorporating sewage sludge into cultivated areas, using wastewater in irrigation, and leaching contaminated soils. However, there are few studies on the ecotoxicological effects of this paraben on edaphic organisms.
Lorena Maihury Santos Tsubouchi, Edson Araújo de Almeida, Diane Scapin, Anna Karolina Gomes Oliveira, Cassiano Aparecido de Souza, Diego Espirito Santo, Carmem Lúcia Henrich, Ana Elisa Maehashi, Gideã Taques Tractz, Craig Allan Downs, Osvaldo Valarini Junior, Regiane da Silva Gonzalez, Elisângela Düsman, Ana Paula Peron   +13 more
wiley   +1 more source

Thermoregulatory, physiological, and intestinal responses to functional waters in heat-stressed rats. [PDF]

Vet World
Al-Dawood A, Al-Shalabi R, Al-Tamimi H, Halalsheh R.   +3 more
europepmc   +1 more source