Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model [PDF]
Journal of Infectious Diseases, 2015 Phylogenetic comparisons of known Marburg virus (MARV) strains reveal 2 distinct genetic lineages: Ravn and the Lake Victoria Marburg complex (eg, Musoke, Popp, and Angola strains). Nucleotide variances of >20% between Ravn and other MARV genomes suggest that differing virulence between lineages may accompany this genetic divergence.
Robert W, Cross +5 more
semanticscholar +4 more sources
Micro‒Global Positioning Systems for Identifying Nightly Opportunities for Marburg Virus Spillover to Humans by Egyptian Rousette Bats [PDF]
Emerging Infectious Diseases, 2023 Marburg virus disease, caused by Marburg and Ravn orthomarburgviruses, emerges sporadically in sub-Saharan Africa and is often fatal in humans. The natural reservoir is the Egyptian rousette bat (ERB), which sheds virus in saliva, urine, and feces ...
Brian R. Amman +13 more
doaj +3 more sources
A rabies virus-vectored vaccine expressing two copies of the Marburg virus glycoprotein gene induced neutralizing antibodies against Marburg virus in humanized mice [PDF]
Emerging Microbes and Infections, 2023 Marburg virus disease (MVD) is a lethal viral haemorrhagic fever caused by Marburg virus (MARV) with a case fatality rate as high as 88%. There is currently no vaccine or antiviral therapy approved for MVD.
Jinhao Bi +12 more
doaj +3 more sources
Evaluation of long-term immunity following inoculation with highly diverse orthomarburgvirus isolates in Egyptian rousette bats (Rousettus aegyptiacus) [PDF]
Journal of VirologyViral coinfections and their impact on long-term immunity represent an understudied area in disease ecology and infectious disease research. Coinfections can influence the host’s susceptibility to future infections, alter host and pathogen population ...
Jessica A. Elbert +7 more
doaj +3 more sources
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2019 Elke Mühlberger
semanticscholar +4 more sources
Shedding of Marburg Virus in Naturally Infected Egyptian Rousette Bats, South Africa, 2017
Emerging Infectious Diseases, 2020 We detected Marburg virus RNA in rectal swab samples from Egyptian rousette bats in South Africa in 2017. This finding signifies that fecal contamination of natural bat habitats is a potential source of infection for humans.
Janusz T. Pawęska +6 more
doaj +2 more sources
Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
doaj +5 more sources
Serologic evidence of orthomarburgviruses and an orthoebolavirus in frugivorous Malagasy bats [PDF]
One Health OutlookRecent outbreaks of Marburg virus disease in regions of sub-Saharan Africa without prior record such as Ghana, Tanzania, Equatorial Guinea, and Rwanda challenge the current understanding of areas at-risk for filovirus spillover.
Marana S. Rekedal +14 more
doaj +2 more sources
Rodent adapted marburg viruses are lethal in ferrets [PDF]
npj VirusesFerrets are highly susceptible to infection with several orthoebolaviruses, including Ebola virus (EBOV), yet they are refractory to infection with the orthomarburgviruses, Marburg virus (MARV) and Ravn virus.
Zachary Schiffman +8 more
doaj +2 more sources
Viruses, 2019 Egyptian rousette bats (Rousettus aegyptiacus) are natural reservoir hosts of Marburg virus (MARV), and Ravn virus (RAVV; collectively called marburgviruses) and have been linked to human cases of Marburg virus disease (MVD). We investigated the clinical
Megan E.B. Jones +10 more
doaj +2 more sources