Results 151 to 160 of about 1,041,724 (230)

Immunostimulant activity of Centella asiatica (ECa 233) on RAW 264.7 macrophages. [PDF]

BMC Complement Med Ther
Manmuan S, Sirirak T, Chuenbarn T.
europepmc   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source

Herbal Formula IM-B Possesses Antioxidant Activities and Reduces Expression of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. [PDF]

Scientifica (Cairo)
Nokkaew N, Ngamdokmai N, Viwatpinyo K, Suwanchaikasem P, Prugsakij W, Pourpongpan P, Warinhomhoun S.   +6 more
europepmc   +1 more source

SHIP1 regulates TREM2 signalling and macrophage functions in a hiPSC‐derived model

The FEBS Journal, EarlyView.
In this study, we characterised the role of SHIP1 in regulating TREM2 signalling and global microglial myeloid functions using human‐induced pluripotent stem cell (hiPSC)‐derived macrophages. Knockout of SHIP1 (SHIP1 KO) in macrophages decreased inflammatory activation and levels of scavenger receptors. SHIP1 KO macrophages also exhibited reduced TREM2
Kim S. Martin, Juliane Obst, Shania Ibarra, Emma J. Murphy, Katerina O. Gospodinova, Emma Mead   +5 more
wiley   +1 more source

Bioactive Peptide Fractions from Mung Bean Protein Hydrolysate: Antioxidant Activity, Anti-Inflammatory Effects, and Immunomodulatory Responses in RAW 264.7 Macrophages. [PDF]

Int J Mol Sci
Chaisan W, Promjeen K, Eawsakul K, Manaspon C, Utama-Ang N.   +4 more
europepmc   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source

Anti-Inflammatory Effects of Sesamin-Loaded Nanoparticles in LPS-Stimulated RAW 264.7 Macrophages. [PDF]

Pharmaceutics
Jantadee K, Kheawfu K, Mangmool S, Chantadee T, Okonogi S, Chittasupho C.   +5 more
europepmc   +1 more source

Advantages and disadvantages of treatment of experimental ARDS by M2-polarized RAW 264.7 macrophages. [PDF]

Heliyon, 2023
Kosyreva AM, Vishnyakova PA, Tsvetkov IS, Kiseleva VV, Dzhalilova DS, Miroshnichenko EA, Lokhonina AV, Makarova OV, Fatkhudinov TH.   +8 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Halodule uninervis ethanolic extract reduces inflammation in LPS-stimulated RAW 264.7 macrophages via NF-κB, STAT3, and MAPK modulation. [PDF]

Sci Rep
Wehbe N, Badran A, Abdallah R, Maresca M, Mesmar JE, Baydoun E.   +5 more
europepmc   +1 more source