Results 141 to 150 of about 1,041,724 (230)

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Intracellular Singlet Oxygen Generation Mediated by Upconversion Nanoparticles in RAW 264.7 Macrophages. [PDF]

ACS Omega
Annunciação Farhat A, Amorín Uscata B, Gidlund MA, Goto H, de Medeiros MHG, Brito HF, Di Mascio P.   +6 more
europepmc   +1 more source

Ajugol Improves Liver Fibrosis by Modulating Bile Acid and Arachidonic Acid Metabolism in Mice

Phytotherapy Research, EarlyView.
Ajujol ameliorates hepatic fibrosis by regulating bile acid metabolism and suppressing inflammatory responses. ABSTRACT Ajugol (AJ), the primary component extracted from the root of Rehmannia glutinosa, exhibits protective effects against metabolic dysregulation and chronic inflammation.
Xia Wei, Fangyuan Wang, Dingqi Zhang, Longhui Zhang, Feipeng Xu, Gaofeng Chen, Hua Zhang, Ping Liu, Wei Liu, Ying Xu   +9 more
wiley   +1 more source

Chemical profiling of Egregia menziesii and anti-inflammatory potential in LPS-activated RAW 264.7 macrophages. [PDF]

Mol Biol Rep
Arroyo-Xochihua O, Sánchez-Medina A, López-Franco Ó, Olivares-Bañuelos TN, Zepeda RC.   +4 more
europepmc   +1 more source

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

IL15.3, a synthetic antimicrobial peptide, attenuates LPS-induced inflammatory responses in RAW 264.7 macrophages via transcriptional and proteomic modulation. [PDF]

PLoS One
Boonmark C, Roytrakul S, Saengyotha F, Tankrathok A, Wanthong A, Daduang J, Daduang S, Chaveerach A, Jangpromma N.   +8 more
europepmc   +1 more source

Safeguarding the Photoluminescence of Silver Sulfide Nanocrystals in Biological Environments via Silica Shielding

Small, EarlyView.
Interactions with biomolecules can alter the photoluminescence of Ag2S nanocrystals, undermining near‐infrared imaging and thermometry. Incorporation into dendritic silica minimizes these interactions and preserves emission intensity, spectral response, and lifetime in plasma and whole blood. This shielding enables more reliable imaging and temperature
Alejandro Hernández Medel, Marina París Ogáyar, Livia Didonè, Peijiang Wang, Ramón Manzorro, Ana B. Hungría, Miriam Granado, Beatriz H. Juárez, Daniel Jaque, Emma Martín Rodríguez, Riccardo Marin, Célia T. Sousa   +11 more
wiley   +1 more source

Comparison of the anti-inflammatory effects of esomeprazole and fexuprazan in lipopolysaccharide-stimulated RAW 264.7 macrophages. [PDF]

BMC Pharmacol Toxicol
Ju GB, Kim SJ, Lee D, Kim MJ, Ko WK, Cho MJ, Sohn S.   +6 more
europepmc   +1 more source

Detection and Inhalation Hazard Assessment of Wear Particles Arising From Abrasion of Market‐relevant Graphene Reinforced Composites

Small, EarlyView.
Abrasion of few‐layer graphene (FLG)–epoxy composites generated respirable particles in which FLG remained fully embedded, as confirmed by correlative HR‑TEM, Raman, and ToF‑SIMS analyses. Advanced lung cell models revealed no cytotoxic or inflammatory responses, and only high‑dose epoxy particles reduced mucociliary clearance.
Govind Gupta, Jimmy Vernaz, Antje Vennemann, Maike Stange, Asmus Meyer‐Plath, Servane Contal, Sarah Zehnder, Ziting Wang, Aline Chary, Stephanie Eitner, Philipp Mueller, Vera M. Kissling, Samuel Constant, Lucie Chupin, Daniel Breitenstein, Birgit Hagenhoff, Tommaso Serchi, Bernadett Boda, Martin Wiemann, Peter Wick, Tina Buerki‐Thurnherr   +20 more
wiley   +1 more source

CURCUMA AERUGINOSA ROXB. EXTRACT INHIBITS THE PRODUCTION OF PROINFLAMMATORY CYTOKINES ON RAW 264.7 MACROPHAGES

Objective: The study explores the potential of Curcuma aeruginosa Roxb. extract for anti-inflammatory properties. Methods: Curcuma aeruginosa Roxb. simplicia was macerated with distilled ethanol.
ALDI, YUFRI, ISMAIL, NOR HADIANI, WAHYUNI, FATMA SRI, HEFNI, DIRA, DACHRIYANUS, SUSANTI, MERI, DEWI, IRENE PUSPA, SYAFRI, SURYATI   +7 more
core   +1 more source