Results 121 to 130 of about 1,041,724 (230)

Somatostatin Regulates Raw 264.7 Cell Cytokine Release [PDF]

, 2008
Immigrant monocytes and resident macrophages propagate the vertebrate innate immune response through cell migration and cytokine production. Monocytes responding to inflammatory challenge migrate into tissues, and as resident macrophages, release a major
Swarup, Shilpa
core  

Benzydamine hydrochloride ameliorates ethanol-induced inflammation in RAW 264.7 macrophages by stabilizing redox homeostasis

Asian Pacific Journal of Tropical Biomedicine
Objective: To evaluate the protective effect of benzydamine hydrochloride against ethanol-induced oxidative stress and inflammation in RAW 264.7 macrophages. Methods: RAW 264.7 macrophages were treated with ethanol (100 mM) and benzydamine hydrochloride (
Tiasha Dasgupta, Venkatraman Manickam
doaj   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Anti‐Inflammatory Effect of Quercetin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic‐Polycytidylic Acid

, 2016
Quercetin (3,3′,4′,5,6‐pentahydroxyflavone) is a well‐known antioxidant and a flavonol found in many fruits, leaves, and vegetables. Quercetin also has known anti‐inflammatory effects on lipopolysaccharide‐induced macrophages.
Young‐Jin Kim, Wansu Park
core   +1 more source

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

Gold nanoparticle-loaded macrophages enhance radiotherapy via immune remodeling in oral cancer

Materials Today Bio
Gold nanoparticles (GNPs) are promising radiosensitizers owing to their high atomic number, but their therapeutic efficacy is often limited by reticuloendothelial system (RES)-mediated clearance and poor tumor accumulation attributable to elevated ...
Hui-Wen Chan, Pei-Wei Sheung, Stella Tzu-Ming Tsao, Chun-Yi Wu, Hui-Yen Chuang   +4 more
doaj   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Effects of terpenoid compounds on inflammation and its related epigenetics in lipopolysaccharide-stimulated RAW 264.7 macrophages

, 2014
萜類化合物(terpenoid compounds)是由異戊二烯單元體所組成的衍生物，普遍存在動物體及植物體中，可分類為單萜類、倍半萜類、雙萜類、三萜類及四萜類。研究指出，萜類化合物具有多種生理功能如抗發炎及抗癌，但對發炎相關的表觀遺傳仍無完整研究，因此本研究篩選具抗發炎潛力的萜類化合物，探討在發炎、預防及治療三種模式下，其對脂多醣(lipopolysaccharide, LPS)刺激RAW 264.7巨噬細胞組蛋白修飾、組蛋白修飾酵素基因表現及DNA甲基轉移酶(DNA ...
Huang, Chun-Yi, 黃淳逸
core  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

4'-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice.

, 2017
4'-Hydroxywogonin (4'-HW), a flavonoid, has been isolated from various plants and shown to inhibit NO production in macrophages. However, the molecular mechanisms and its in vivo activity have not been determined.
Shuo Zhang, Zhang, Shuo, Fangfang Xu, Zhang, Gu-Fang, Zhang, Xiuli, Ye, Richard D., Chao Fan, Yu, Yang, Fan, Chao, Yang Yu, Lei Sun, Richard D Ye, Yan Zhang, Wu, Le-Hao, Le-Hao Wu, Xu, Fangfang, Sun, Lei, Zhang, Yan, Xiuli Zhang, Gu-Fang Zhang   +19 more
core   +1 more source