Results 11 to 20 of about 28,464 (119)

Genomic characterization and histologic analysis of uterine leiomyosarcoma arising from leiomyoma with bizarre nuclei. [PDF]

J Pathol
Abstract Leiomyoma with bizarre nuclei (LM‐BN) is a rare variant of leiomyoma with a benign clinical course. In contrast, leiomyosarcoma (LMS) is a high‐grade, malignant neoplasm characterized by high recurrence rates and poor survival. While LM‐BN and LMS show distinct morphologies, they share similar immunoprofiles and molecular alterations, with ...
Felicelli C, Lu X, Coty-Fattal Z, Feng Y, Yin P, Schipma MJ, Kim JJ, Jennings LJ, Bulun SE, Wei JJ.   +9 more
europepmc   +2 more sources

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract

Cancer Communications, Volume 42, Issue 12, Page 1367-1386, December 2022., 2022
Abstract Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of GI‐NECs.
Huanwen Wu, Zicheng Yu, Yueping Liu, Lei Guo, Lianghong Teng, Lingchuan Guo, Li Liang, Jing Wang, Jie Gao, Ruiyu Li, Ling Yang, Xiu Nie, Dan Su, Zhiyong Liang   +13 more
wiley   +1 more source

Current status of precision oncology in adult glioblastoma. [PDF]

Mol Oncol
This review summarizes the current status of precision oncology – targeted therapies based on individual genetic profiles – in glioblastoma. Although some treatments show promise, their applicability and effectiveness remain limited, underlining the need for innovative approaches.
Weller J, Potthoff AL, Zeyen T, Schaub C, Duffy C, Schneider M, Herrlinger U.   +6 more
europepmc   +2 more sources

Analysis of Surgical Pathology Data in the HIRA Database: Emphasis on Current Status and Endoscopic Submucosal Dissection Specimens [PDF]

Journal of Pathology and Translational Medicine, 2016
Background: In Korea, medical institutions make claims for insurance reimbursement to the Health Insurance Review and Assessment Service (HIRA). Thus, HIRA databases reflect the general medical services that are provided in Korea.
Sun-ju Byeon, Woo Ho Kim
doaj   +1 more source

Clinico-histopathological correlation of skin biopsies in leprosy

Journal of Pathology of Nepal, 2013
Background: In leprosy, there is a range of varied clinicopathologic manifestations and the diagnosis is made from adequate clinical information combined with bacilloscopy and histopathology which helps in diagnosing different types of leprosy and ...
U Manandhar, RC Adhikari, G Sayami
doaj   +1 more source

Dysembryoplastic Neuroepithelial Tumors [PDF]

Journal of Pathology and Translational Medicine, 2015
Dysembryoplastic neuroepithelial tumor (DNT) is a benign glioneuronal neoplasm that most commonly occurs in children and young adults and may present with medically intractable, chronic seizures.
Yeon-Lim Suh
doaj   +1 more source

Clear Cell Adenocarcinoma Arising from Adenofibroma in a Patient with Endometriosis of the Ovary [PDF]

Journal of Pathology and Translational Medicine, 2016
Ovarian clear cell adenocarcinomas (CCACs) are frequently associated with endometriosis and, less often with clear cell adenofibromas (CCAFs). We encountered a case of ovarian CCAC arising from benign and borderline adenofibromas of the clear cell and ...
Inju Cho, Sung-Chul Lim
doaj   +1 more source

Down-regulation of SOCS6: an unfavorable prognostic factor for gastrointestinal stromal tumor proven by survival analysis

Diagnostic Pathology, 2021
Background Many studies reporting that down-regulation of SOCS6 plays vital roles in promoting progression of malignant tumors have been published. The present study was performed to evaluate whether SOCS6 was significantly associated with prognosis of ...
Jun Ouyang, Tailai An, Yan Wang, Xiaofang Lu, Yawei Zhang, Xiaokun Wang, Xinhua Zhang, Changhua Zhang   +7 more
doaj   +1 more source

Electrogenic reduction of the primary electron donor P700+ in photosystem I by redox dyes [PDF]

The kinetics of reduction of the photo-oxidized primary electron donor P700+ by redox dyes N,N,N′,N′-tetramethyl-p-phenylendiamine, 2,6-dichlorophenol-indophenol and phenazine methosulfate was studied in proteoliposomes containing Photosystem I complexes
Golbeck, John H., Gourovskaya, Kira N., Mamedov, Mahir D., Semenov, Alexey Yu., Vassiliev, Ilya R.   +4 more
core   +1 more source

Metastatic breast carcinoma uncovered in an otherwise unremarkable “random colon biopsy”

Human Pathology: Case Reports, 2016
Breast cancer is one of the most devastating cancers afflicting women, being a main cause of cancer related death. Approximately 50% of these patients have developed regional or distant metastases at the time of diagnosis; hence, an early diagnosis and ...
Mike Black, Ardeshir Hakam, Cynthia Harris, Kun Jiang   +3 more
doaj   +1 more source