Results 281 to 290 of about 107,123 (321)

Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction

Science China Life Sciences, 2022
Fen-Ting Liu, Lin Fu, Hanry Yu
exaly   +2 more sources

Supramolecular Integration of Multifunctional Nanomaterial by Mannose-Decorated Azocalixarene with Ginsenoside Rb1 for Synergistic Therapy of Rheumatoid Arthritis.

ACS Nano, 2023
The complexity and progressive nature of diseases require the exploitation of multifunctional materials. However, introducing a function inevitably increases the complexity of materials, which complicates preparation and decreases reproducibility. Herein,
Shihui Li, Juan-Juan Li, Yingxin Zhao, Meng-Meng Chen, Shan-Shan Su, Shun-Yu Yao, Ze-Han Wang, Xin-Yue Hu, Wen-Chao Geng, Wei Wang, Ke-Rang Wang, Dong-Sheng Guo   +11 more
semanticscholar   +1 more source

The Neuroprotective Effect of Ginsenoside Rb1 on the Cerebral Cortex Changes Induced by Aluminium Chloride in a Mouse Model of Alzheimer's Disease: A Histological, Immunohistochemical, and Biochemical Study.

Journal of Chemical Neuroanatomy, 2023
Alzheimer's disease (AD) is one of the most common types of dementia among neurodegenerative disorders characterized by attention deficits and memory loss.
A. Shalaby, S. Alnasser, Dina Ahmed Khairy, M. Alabiad, Mohammed Alorini, Fatima A Jaber, S. Tawfeek   +6 more
semanticscholar   +1 more source

Ginsenoside Rb1 alleviated concanavalin A-induced hepatocyte pyroptosis by activating mitophagy.

Food & Function, 2023
Pyroptosis is characterized as gasdermin-mediated programmed death and has received substantial attention in recent years. Excessive hepatocyte pyroptosis could induce acute liver injury, and there is a lack of efficient natural compounds to alleviate it.
Qian Zhang, Jinping Hu, Ankang Mao, Meitong Liu, S. Guan, Jing Lu   +5 more
semanticscholar   +1 more source

Ginsenoside Rb1 Inhibits Cardiomyocyte Autophagy via PI3K/Akt/mTOR Signaling Pathway and Reduces Myocardial Ischemia/Reperfusion Injury.

The American Journal of Chinese Medicine, 2021
Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage in acute myocardial infarction, and its treatment remains a clinical challenge.
Guo-Wei Qin, Pan Lu, Li Peng, Wei Jiang
semanticscholar   +1 more source

Ginsenoside Rb1 protects against diabetes-associated metabolic disorders in Kkay mice by reshaping gut microbiota and fecal metabolic profiles.

Journal of Ethnopharmacology, 2022
ETHNOPHARMACOLOGICAL RELEVANCE Panax quinquefolius Linn. is one of the most valuable herbal medicine in the world for its broad health benefits, including anti-diabetes.
Rongrong Zhou, Dan He, Haichao Zhang, Jing Xie, Shuihan Zhang, Xuefei Tian, Hongliang Zeng, Yuhui Qin, Luqi Huang   +8 more
semanticscholar   +1 more source

Molecular alterations in retinoblastoma beyond RB1

Experimental Eye Research, 2021
Retinoblastoma is the most common malignant ocular tumor in children. Although RB1 alterations are most frequently involved in the etiology of retinoblastoma, candidate driver events and somatic alterations leading to cell transformation, tumor onset and progression remain poorly understood.
Vanessa, Mendonça, Anna Claudia, Evangelista, Bruna, P Matta, Miguel Ângelo, M Moreira, Paulo, Faria, Evandro, Lucena, Héctor N, Seuánez   +6 more
openaire   +2 more sources

Ginsenosides Rg1, Rb1 and rare ginsenosides: Promising candidate agents for Parkinson's disease and Alzheimer's disease and network pharmacology analysis.

Pharmacological Research
Ginseng has been commonly used as a traditional Chinese medicine in Asian countries for thousands of years. Ginsenosides are the main pharmacologically active ingredients isolated from ginseng and have neuroprotective effects in the treatment of ...
Min-Jie Jiang, Jiaxin Chi, Yifan Qiao, Jinpeng Wang, Zhixin Zhang, Jia Liu, Xinhao Sheng, Liangjie Yuan   +7 more
semanticscholar   +1 more source

Ginsenoside Rb1 ameliorates heart failure through DUSP-1-TMBIM-6-mediated mitochondrial quality control and gut flora interactions.

Phytomedicine
BACKGROUND There is currently no specific therapeutic drug available for heart failure in clinical practice. Numerous studies have validated the efficacy of Ginsenoside Rb1, an active component found in various herbal remedies used for heart failure ...
Xiangyi Pu, Qin Zhang, Jinfeng Liu, Yanli Wang, Xuanke Guan, Qiaomin Wu, Zhiming Liu, Ruxiu Liu, Xing Chang   +8 more
semanticscholar   +1 more source

Platelet membrane-cloaked selenium/ginsenoside Rb1 nanosystem as biomimetic reactor for atherosclerosis therapy.

Colloids and Surfaces B: Biointerfaces, 2022
Cardiovascular disease remains the dominant contributor to human mortality, and the main etiology of which is atherosclerosis (AS). Enhancing the targeted ability of nanosystem and improving plaque stability are critical challenges for the current ...
Mengdie Yin, Juanfang Lin, Mingyue Yang, Chao Li, Pengyu Wu, Jun-Jie Zou, Yajing Jiang, Jing-Wei Shao   +7 more
semanticscholar   +1 more source